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A cover letter is required for consideration for this position and should be attached as the first page of your resume. The cover letter should address your specific interest in the position and outline skills and experience that directly relate to this position.

Job Summary

Seeking a qualified individual to work in the Center for Chemical Genomics (CCG), which is part of the Life Sciences Institute at U-M. The CCG is the home of high throughput (HT) biology, pharmacology and chemical genomics at U-M. The position includes working collaboratively with principle investigators, postdoctoral fellows and graduate students to first optimize and validate HT assays and to work collaboratively using these HT assays to screen the CCG’s chemical collection and/or RNAi library for probes to address basic science and/or translational research questions. Experience using HT assay formats and technology is mandatory. Automation experience is not a prerequisite for the job.

Responsibilities*

  • Design and perform assay validation and optimization experiments for 96 and 384-well high throughput (HT) assays
  • Direct responsibility for running pilot, subset and full file HT assays
  • Direct responsibility for monitoring the integrity of data generated by HT assays
  • Direct responsibility for analysis of data using standard statistical methods e.g. calculation of EC50 using a 3 or 4 parameter fit.
  • Direct responsibility for mining data for insight, trends, and anomalies
  • Review and critique reports and analysis of other researchers and conduct ongoing, periodic and final analysis of data
  • Write and collaborate with other researchers on manuscripts, abstracts, technical reports and other publications of research findings
  • Collaborate with researchers on long-range plan for overall research project acting as expert in specialized area
  • Co-leadership of HT research project teams
  • Supervise and review the work of graduate students and post doctoral scholars in methods and procedures necessary to achieve goals of HT projects
  • Present data at lab meeting and when appropriate at local and national meetings
  • Assure compliance safety programs
  • Analyze, compare and evaluate new technical options for research experiments with the authority to make independent decisions

Required Qualifications*

  • Masters degree in a field of biomedical science
  • Minimum of 5 years of experience doing biochemistry, cell-biology or molecular biology research including validating and running assays in 96- or 384-well format
  • Proven experience validating and running cell-based assays in 96- or 384-well format
  • Excellent interpersonal and organizational skills
  • Excellent written and oral communication skills
  • Demonstrated ability to teach and/or train students, junior laboratory personnel in laboratory techniques and/or protocols
  • Ability to work independently or as a member of a team
  • Excellent attendance, ability to prioritize appropriately and exercise good judgment  
  • Evidence of qualifications is provided through performance reviews, personal interview and/or reference checks

Desired Qualifications*

  • Doctoral Degree in a field of biomedical science
  • Experience with GPCRs, ion channels, growth factor receptor and/or druggable gene targets
  • Demonstration of management experience
  • Familiarity with University of Michigan research administration, policies and procedures

Background Screening

The University of Michigan conducts background checks on all job candidates upon acceptance of a contingent offer and may use a third party administrator to conduct background checks. Background checks will be performed in compliance with the Fair Credit Reporting Act.

Application Deadline

Job openings are posted for a minimum of seven calendar days. This job may be removed from posting boards and filled anytime after the minimum posting period has ended.

U-M EEO/AA Statement

The University of Michigan is an equal opportunity/affirmative action employer.