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Responsibilities*

Post-doctoral positions are available for scientists in molecular biology, biology, biochemistry, and chemistry to perform clinical translation research. Join a multi-disciplinary research team in the emerging field of molecular imaging at the University of Michigan (https://sites.google.com/a/umich.edu/wang_lab). This highly collaborative group aims to develop innovative imaging technologies to improve the practice of medicine. Projects focus on the development, characterization, and validation of peptides for clinical use as specific molecular probes for early detection and image-guided therapy of cancer. Projects focus on 1) use of sophisticated genomic tools to identify early targets that arise in the development of esophageal cancer, 2) development of peptide dimers to produce multivalent ligand-target interactions for improved binding performance and detection of early targets at low levels of expression, and 3) clinical translation of integrated imaging approach. High resolution endoscopic, confocal, multiphoton, and photoacoustic imaging systems will be used to study small animal models. Our goal is to perform real-time detection of pre-malignant mucosa (dysplasia) in the biliary tract, colon, esophagus, liver, pancreas, and stomach. FDA-regulated clinical studies will be performed to validate peptide performance in human patients in collaboration with academic physicians. The University of Michigan is committed to diversity and equality in education and employment, and is an ideal training ground for postdocs who want to further develop their skills in pursuit of a career in academia or industry.

Required Qualifications*

Candidates with a Ph.D. in molecular biology, structural biology, cell biology, genetics, biochemistry, chemistry, microbiology, immunology, pharmacology, or related discipline are invited to apply.  Experience in molecular biology techniques is required, including any of these areas:  cell culture, microscopy, flow cytometry, siRNA knockdown, structural protein modeling, ELISA, PCR, RT-PCR, Western blot, immunohistochemistry, and immunofluorescence.  Experience with handling of small animals, including mice and rats, is desirable.  Salary is commensurate with training and experience.

Work Locations

The laboratory is located in the Biomedical Science Research Building (BSRB) between the University of Michigan Medical Center and the science campus.  Pre-clinical studies are performed in the Center for Molecular Imaging (CMI) (http://www.med.umich.edu/cmi), and clinical trials are conducted in the hospital Medical Procedures Unit.

Background Screening

Michigan Medicine conducts background screening and pre-employment drug testing on job candidates upon acceptance of a contingent job offer and may use a third party administrator to conduct background screenings.  Background screenings are performed in compliance with the Fair Credit Report Act.

Contact Information

Along with applying to this posting, candidates should submit CV and contact information by email:  Thomas D. Wang, M.D.,Ph.D., Professor of Medicine, H. Marvin Pollard Collegiate Professor of Endoscopy Research, University of Michigan, Ann Arbor, MI 48109-2200, Email: tdwangmd@gmail.com

Mission Statement

Michigan Medicine improves the health of patients, populations and communities through excellence in education, patient care, community service, research and technology development, and through leadership activities in Michigan, nationally and internationally.  Our mission is guided by our Strategic Principles and has three critical components; patient care, education and research that together enhance our contribution to society.

Application Deadline

Job openings are posted for a minimum of seven calendar days. This job may be removed from posting boards and filled anytime after the minimum posting period has ended.

U-M EEO/AA Statement

The University of Michigan is an equal opportunity/affirmative action employer.