Research fellow in a laboratory conducting primary basic research in the broad area of molecular genetics, more specifically in the areas of genomic instability and copy number variation in the germline and cancer, chromosome fragile sites, replication-transcription conflicts, bioinformatics.
This new hire will conduct basic research using mouse and human cells into mechanisms of genomic instability under replication and transcription stress. The individual will be responsible for (i) experimental design, execution and interpretation, (ii) identification and implementation of new experimental directions within the scope of the project, (iii) working effectively as part of a laboratory team, including assisting colleagues in skill development as needed, (iv) presenting ongoing and finished research at group meetings and at national conferences, (v) helping to prepare research publications and grant applications, and (vi) helping with routine laboratory maintenance activities such as ordering supplies and safety monitoring.
This position requires a PhD or MD and at least three years of dedicated laboratory training experience, such as during graduate school. This experience must be in an area of general relevance to the project, such as molecular biology, molecular genetics, genomics or bioinformatics, and must include a documented ability to execute routine laboratory techniques in molecular biology and mammalian cell culture. The individual must have been a primary author on at least one prior research publication in these topic areas in a peer-reviewed research journal. Reference letters documenting research excellence will be required from the previous research mentor and at least one other referee.
Desired additional qualifications include (i) experience and a strong abiding interest in molecular genetic mechanisms of genomic instability, (ii) specific research experience with molecular mechanisms of DNA repair, replication and/or transcription, (iii) more than one peer-reviewed research publication as primary author in these areas, and (iv) direct experience with bioinformatics and the computational processing of large-scale genomic data.
Week day business hours, occasional evening and weekends.
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