Seeking an experienced research associate who is energetic, enthusiastic, and enjoys collaborative and independent science.
The focus of the lab is stem cell biology and epigenetics. Since eye diseases are the first human disorders for which clinical trials for embryonic and induced pluripotent stem cell-derived tissue transplantation are being conducted, you will be at the cutting edge of a technology important for regenerative medicine.
The primary job responsibility for this position is to move the research project forward through experimental work, critical thinking, and coordinating work of others within the lab and with collaborators within the university. Specific tasks include human and mouse stem cell, primary, and cancer cell culture, protein purification, flow cytometry, transgenic mouse colony management, RNAi, CRISPR/Cas9 gene editing, RNA-seq/ChIP-seq and other genome wide assays, and basic molecular biology techniques such as cloning, transfection, and viral transduction. As part of their career development, this person will help to supervise and mentor others within the laboratory.
Expected to help lead and manage day to day operations of several projects in the laboratory (to which s/he is assigned), including completion of aims/goals set out in grant applications, and regular lab meetings. S/he will also work directly with the principal investigator on developing research goals and writing portions of research proposals and manuscripts. S/he will be responsible for making presentations of research findings at lab and group meetings and national meetings, if appropriate.
Duties for this position include interdisciplinary interactions with Department of Pathology, Pluripotent Stem Cell Cores, as well as:
- Bachlelor's degree required with 5-6 years of related experience
- Other previous laboratory experience required includes strong molecular biology background: mouse genotyping and colony management, western blotting, protein immunoprecipitation, PCR, RNA interference, flow cytometry, bacterial and mammalian protein expression, and purification, viral transduction, electroporation, cloning.
- Manuscript preparation.
- Ability to work and troubleshoot independently.
- Must be proficient in Microsoft Office, Prism, and Adobe software, and knowledge of or capable of learning basic bioinformatics techniques.
- Highly motivated, detail oriented, responsible individual with excellent communication and organizational skills.
- Previous laboratory experience (1 to 3 years) with pluripotent stem cell culture (mouse and human) and use of CRISPR/Cas9 technology is required.
- The qualified candidate will have earned a masters or doctoral degree in the biological sciences, specifically stem cells, epigenetics, bioinformatics, or a closely related field.
Michigan Medicine conducts background screening and pre-employment drug testing on job candidates upon acceptance of a contingent job offer and may use a third party administrator to conduct background screenings. Background screenings are performed in compliance with the Fair Credit Report Act.
The Kellogg Eye Center seeks to improve lives through curing, preventing and treating eye disease. Guiding Principles: Teamwork, Caring, Innovation, and Integrity
Job openings are posted for a minimum of seven calendar days. This job may be removed from posting boards and filled anytime after the minimum posting period has ended.
U-M EEO/AA Statement
The University of Michigan is an equal opportunity/affirmative action employer.