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A cover letter is required for consideration for this position and should be attached as the first page of your resume. The cover letter should address your specific interest in the position and outline skills and experience that directly relate to this position.

Job Summary

Laboratories of Uhn-Soo Cho ( www.uscho-lab.com/ ) and Kaushik Ragunathan (ragunathanlab.org/ ) at University of Michigan Medical School are seeking a joint-appointed Research Lab Specialist Intermediate (50/50 percent shared by two labs) with dynamic interests in solving important biological questions using structural, biochemical, and yeast genetic approaches. University of Michigan provides an exciting environment to learn and conduct various structural biological techniques.

The Cho lab conducts x-ray crystallography and cryo-EM to determine the structures of biologically important proteins to understand basic mechanisms of epigenetic inheritance mediated by histone chaperones at high-resolution. The Ragunathan lab focuses on fission yeast genetics/epigenetics and single-molecule FRET.

Responsibilities*

Lab responsbilities include design and conduct research focused on epigenetics using fission yeast genetics and single-molecule FRET. Solve important biological questions using structural, biochemical, and yeast genetic approaches.

Supervise, train and orient temporary lab staff, undergraduate and graduate students in equipment operation and laboratory techniques. Extensive knowledge of operation of lab equipment, including limitations and outcomes. Contribution to overall scientific efforts of the laboratory by advising, consulting and assisting laboratory staff as needed.

Placement and management of lab stocks and reagents. Will be expected to provide lab management support in the form of routine laboratory maintenance (inventory-keeping, preparation of stocks and buffers, etc.), record keeping, and compliance with University of Michigan regulations. Execution of lab policies, ensuring compliance in lab safety and OSEH regulations.

Perform statistical analysis, literature searches, write-up results for publications and generate ideas for grant applications.

Required Qualifications*

  • A Bachelor's degree in Biology or closely related field, with at least 4-5 years relevant research experience. 
  • A qualified candidate should have more than 4 years of  experience in the area of crystallography, cryo-EM, or biophysics as well as fission yeast genetics with knowledge and experience in basic molecular biology, fission yeast genetics, and protein expression/purification.
  • Experiences in x-ray crystallography or cryo-EM as well as fission yeast genetics are strongly preferred.
  • Other requirements include excellent oral and written communication skills in English, effective judgment and problem solving and a willingness to work within a group.
  • A successful candidate will be highly motivated, able to efficiently multi-task, and able to work independently and committed to academic biomedical research.
  • Meticulous attention to detail and the ability to prioritize and manage time are crucial skills for this position.
  • Some evening and weekend work may be required.

Desired Qualifications*

  • Doctoral degree in the Biological Sciences with at least 5 years’ experience with yeast and mammalian research is desired.
  • Experience in bacterial protein expression and protein purification techniques is desired.
  • Experience in lab administration, lab management and student training is preferred.

Additional Information

Please visit the Cho lab (www.uscho-lab.com/) and the Ragunathan lab (ragunathanlab.org/ ) websites to learn more about the labs.  

Background Screening

Michigan Medicine conducts background screening and pre-employment drug testing on job candidates upon acceptance of a contingent job offer and may use a third party administrator to conduct background screenings.  Background screenings are performed in compliance with the Fair Credit Report Act.

U-M EEO/AA Statement

The University of Michigan is an equal opportunity/affirmative action employer.