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How to Apply

A cover letter is required for consideration for this position and should be attached as the first page of your resume. The cover letter should address your specific interest in the position and outline skills and experience that directly relate to this position.

Job Summary

Will be responsible for the operation and management of Dr. Simon Hogan's laboratory in the Mary H. Weiser Food Allergy Center. Will have an active role in the design, execution and outcome assessment of Dr. Hogan's research projects and will assist him in the development of research goals. 

Responsibilities*

Independently implement technical procedures for assignments including:

  • Perform animal experimentation with respect to food allergy and anaphylaxis including bone marrow transplant and train and supervise lab members in animal experiments.

  • Maintaining mouse colony including genotyping of complex transgenics in tissue specific knockout mice.

  • Purify immune cells from gastrointestinal tissue and supervise/train lab members in these experiments.

  • Perform genetic manipulation and genetic analysis of immune and gastrointestinal cells (in vitro and in vivo) and supervise/train lab members in these experiments.

  • Perform electrophysiological analyses of gastrointestinal tissue and supervise/train lab members in these experiments.

  • Perform flow cytometry, immunohistochemistry and fluorescence microscopy of gastrointestinal sections and immune cells and supervise/train lab members in these experiments.

  • Participate in formulating research methods and suggest options for improving quality.

  • Writing and maintaining regulatory protocols (IACUC, IBC and IRB).

  • Make recommendations on best technical approaches to investigate a scientific problem.

  • Assist other team members in their projects.

  • Participate in laboratory meetings.

  • Interact with collaborators as necessary to provide interpretation of study results.

  • Communicate and make recommendations to other scientists in the team.

  • Independently participate in academic authorship of manuscripts and grants related to lab work.

  • Responsible for accurate record keeping.

  • Train personnel in existing laboratory techniques and procedures, explain and demonstrate technology and equipment capabilities, operation limitation and outcomes.

  • Purchasing consumables and reagents and maintenance of inventory.

  • Independently implement technical procedures for assignments including:

  • Perform animal experimentation with respect to food allergy and anaphylaxis including bone marrow transplant and train and supervise lab members in animal experiments.

  • Maintaining mouse colony including genotyping of complex transgenics in tissue specific knockout mice.

  • Purify immune cells from gastrointestinal tissue and supervise/train lab members in these experiments.

  • Perform genetic manipulation and genetic analysis of immune and gastrointestinal cells (in vitro and in vivo) and supervise/train lab members in these experiments.

  • Perform electrophysiological analyses of gastrointestinal tissue and supervise/train lab members in these experiments.

  • Perform flow cytometry, immunohistochemistry and fluorescence microscopy of gastrointestinal sections and immune cells and supervise/train lab members in these experiments.

  • Participate in formulating research methods and suggest options for improving quality.

  • Writing and maintaining regulatory protocols (IACUC, IBC and IRB).

  • Make recommendations on best technical approaches to investigate a scientific problem.

  • Assist other team members in their projects.

  • Participate in laboratory meetings.

  • Interact with collaborators as necessary to provide interpretation of study results.

  • Communicate and make recommendations to other scientists in the team.

  • Independently participate in academic authorship of manuscripts and grants related to lab work.

  • Responsible for accurate record keeping.

  • Train personnel in existing laboratory techniques and procedures, explain and demonstrate technology and equipment capabilities, operation limitation and outcomes.

  • Purchasing consumables and reagents and maintenance of inventory.

Required Qualifications*

  • Bachelor's Degree in a recognized field of science directly related to the position.

  • Four to five years of directly related laboratory experience.

  • Exceptional work ethic in a highly competitive environment.

  • Ability to communicate clearly the results of his/her experiments to other team members.

  • Working knowledge of principles of animal husbandry, mouse genetics, molecular biology, microbiology and immunology.

  • Proficiency in Microsoft Word, PowerPoint, Excel, flowjo and GraphPad Prism.

  • Familiarity with basic laboratory instrumentation and maintenance of laboratory equipment.

  • Proficient in record keeping.

  • A solid command of tissue culture and in conducting studies in a BSL-2 environment.

  • Evidence of qualifications is provided by previous employment, references, performance evaluations and/or personal interview.

Desired Qualifications*

  • Master’s Degree or PhD in a recognized field of science directly related to the position.

  • Minimum five years’ of directly related laboratory experience.

  • Familiarity with University research administration policies and procedures.

  • Hands on skills and experience in immunological, biochemical and molecular techniques including isolation of primary cells, quantification of mRNA (qPCR). cloning, and protein expression, ELISA, western blotting, biochemical and cellular screening assays.

  • Experience with animal models and immune cell purification from tissue compartments (gastrointestinal).

  • Experience at writing and maintaining regulatory protocols (IACUC, IBC and IRB).

Background Screening

Michigan Medicine conducts background screening and pre-employment drug testing on job candidates upon acceptance of a contingent job offer and may use a third party administrator to conduct background screenings.  Background screenings are performed in compliance with the Fair Credit Report Act.

Application Deadline

Job openings are posted for a minimum of seven calendar days.  This job may be removed from posting boards and filled anytime after the minimum posting period has ended.

U-M EEO/AA Statement

The University of Michigan is an equal opportunity/affirmative action employer.