The Michigan Center for Translational Pathology (MCTP) is seeking a bioinformatician / computational biologist to support our cancer research program. This
position will be centered on contributing advanced data analyses to interdisciplinary research projects, including: carrying out statistical and bioinformatics
analyses, implementing algorithms for genomic analyses, developing computational workflows, and building visualization tools. As part of a dynamic team, the
position will develop and apply advanced computational techniques to learn about the underlying biology and to guide experimental work.
The successful candidate should be comfortable analyzing large data sets (demonstrated experience in the analysis of real-world datasets required), have
experience in software development, and possess strong interpersonal and communication skills. The ideal candidate will use their computational skills,
biological knowledge, understanding of statistics, and creativity to help us understand complex genomic data sets. Proficiency in utilizing and integrating data
from an array of public resources such as ENCODE, TCGA or COSMIC and ability to synthesize and present conclusions from complex analyses in a clear and
visually compelling way will be paramount for this role.
This position offers sick and Vacation Days
- Conduct pathology research using bioinformatics theory and methods.
- Implement algorithms for genomic analyses, develop computational workflows, and build visualization tools.
- Apply advanced computational techniques to learn about the underlying biology and to guide experimental work.
- Utilize and integrate data from an array of public resources, such as ENCODE, TCGA or COSMIC.
- Bachelor’s degree in a recognized field of science or learning which is directly related to the duties of this position. Candidates with experience in
- bioinformatics strongly preferred.
- Demonstrated 2-year experience in the statistical / computational analysis of large and / or complex datasets (candidates not meeting this
- requirement will not be considered).
- Substantial expertise in one or more of Python, R, C/C++, or Java as demonstrated by the ability to develop high-quality scientific programs.
- Practical knowledge of statistical techniques.
- Experience in working on Unix/Linux systems (shell scripting, basic system administration)
- Ability to multi-task, prioritize efforts, and execute independently- and collaboratively-developed ideas in a fast-paced environment.
- Advanced degree in a quantitative discipline. PhD degree strongly preferred.
- Experience and/or familiarity with molecular cancer research. ?
- Experience with the analysis of data from high-throughput molecular profiling techniques such next-generation sequencing, microarray, or mass-spec.
- Experience with next-gen sequencing data, including functional genomic assays (e.g. RNA-Seq, ChIP-seq, DNA methylation).
- Experience with standard bioinformatics software tools and packages e.g. Bioconductor
- Fluency in understanding code written in multiple languages including C/C++, Java, Python and R.
- Working knowledge of laboratory techniques in molecular biology, cell biology, biochemistry, and genetics.
- A solid understanding of statistics and experience in the implementation of machine learning and statistical inference algorithms.
- Experience in cloud computing (GCE or AWS)
- A strong publication record.
M-F, 8:00 - 5:00
Michigan Medicine Cancer Center; Ann Arbor
MCTP employs genomic, proteomic, and bioinformatic approaches on clinical biospecimens to identify novel cancer biomarkers and therapeutic
targets. The mission of the Center is to facilitate the discovery, validation, and implementation of candidate target genes/proteins in cancer diagnosis, prognosis, and therapy. The Center employs a multi-disciplinary approach, engaging talent from diverse disciplines ranging from medicine, pathology, bioinformatics, biostatistics, engineering, cytogenetics, and molecular therapeutics.
Michigan Medicine conducts background screening and pre-employment drug testing on job candidates upon acceptance of a contingent job offer and may use a third party administrator to conduct background screenings. Background screenings are performed in compliance with the Fair Credit Report Act.
Michigan Medicine improves the health of patients, populations and communities through excellence in education, patient care, community service, research and technology development, and through leadership activities in Michigan, nationally and internationally. Our mission is guided by our Strategic Principles and has three critical components; patient care, education and research that together enhance our contribution to society.
Job openings are posted for a minimum of seven calendar days. This job may be removed from posting boards and filled anytime after the minimum posting period has ended.
U-M EEO/AA Statement
The University of Michigan is an equal opportunity/affirmative action employer.