The Michigan Center for Translational Pathology (MCTP) is seeking a histopathologist for a Research Fellow position. MCTP integrates genomic, proteomic, and bioinformatics approaches on clinical biospecimens to identify novel cancer biomarkers and therapeutic targets. The mission of the Center is to facilitate the discovery, validation, and implementation of candidate target genes/proteins in cancer diagnosis, prognosis, and therapy. The Center employs a multi-disciplinary approach, engaging talent from diverse disciplines ranging from medicine, pathology, bioinformatics, biostatistics, engineering, cytogenetics, and molecular therapeutics.
We are looking for a histopathologist to work with the MCTP clinical and research groups to develop tissue based assays, biomarker discovery and follow up functional studies using fluorescence in situ hybridization (FISH), immunohistochemistry (IHC), RNA in situ hybridization (RNA-ISH), laser capture microdissection (LCM), and cell based assays and technologies. The successful candidate must be capable of thriving in a fast-paced dynamic environment. The candidate will work as part of a team to perform routine and complex laboratory experimental procedures under the supervision of the Principal Investigators and/or higher level research staff. The position will participate in research projects in a collaborative and interdisciplinary team environment.
Duties for this position include, but are not limited to, review human/mouse formalin-fixed paraffin embedded (FFPE) and frozen tissue H&E slides. Independently design, plan, execute and interpret experiments in the areas of IHC, FISH, and RNA-ISH. Independently evaluate and score IHC and RNA-ISH slides. Make tissue microarrays. Perform LCM. Participate in procuring samples from rapid autopsy. Work closely with SPORE team on ongoing clinical and research projects. Perform bench work as needed to ensure timely completion of work. May be required to develop, execute, or validate new procedures. Organize databases for test validation. Work closely with directors, supervisor, and section leaders in test development and trouble-shooting.
- Applicants must have completed a graduate degree (MD and/or PhD) with relevant experience in Surgical Pathology, Cytogenetics, Biology or Clinical Laboratory Science.
- Experience in histology, immunohistochemistry, RNA-ISH, FISH and LCM is preferred.
- Familiar with various microscope imaging software.
- Ability and willingness to learn and implement novel experimental techniques.
- Basic computer skills and familiarity with PC (Windows) are required.
- Excellent teamwork and fluent verbal and written English communication skills are essential.
- Strong organizational and multi-tasking skills.
- Experience in pathology residency and/or fellowship program training
- Fluency in English and teamwork skills to work in a multidisciplinary environment are important.
- This position will require self-initiative and ability to work without close supervision
5316 CCC - Ann Arbor
Term Limited Job: One-year postdoc with option to renew
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