The laboratory of Dr. Wenjing Wang at the Life Sciences Institute of the University of Michigan is seeking a postdoctoral fellow to design novel optogenetic tools for manipulating endogenous protein’s functions (http://www.lsi.umich.edu/labs/wenjing-wang-lab).
The Wang lab is interested in developing a wide array of next generation optogenetic tools for studying neuroscience and cell biology. During her postdoctoral research, Dr. Wang engineered an optogenetic tool that can mark the neurons that are firing during a specific time window with a reporter gene expression. She also designed a new reporter for detecting protein-protein interactions with a temporal control that can be used for detecting GPCR activation and neurotransmitter release. The Wang lab will continue to design optogenetic tools that can provide precise temporal and spatial control but sensitive to different colors of light. We will use state-of-the-art protein engineering methods, such as directed evolution, to optimize the new tools. Mammalian cell culture and animal models will be used to test the new tools.
We are looking for highly motivated and ambitious young scientists with a doctoral degree in Chemistry or Biology or related majors (e.g. Biochemistry, Bioengineering, Molecular Biology, Biophysics and Neuroscience). The successful candidate is expected to conduct research independently under the supervision of the PI. Applicants with expertise in areas including but not limited to, molecular biology (especially molecular cloning and protein expression), directed evolution, imaging, mammalian cultures and model studies are welcome to apply.
Interested applicants please contact firstname.lastname@example.org with (1) a cover letter describing research experiences and interests; (2) Curriculum Vitae (CV); and (3) Contact information for three letters of reference.
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