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How to Apply

A cover letter is required for consideration for this position and should be attached as the first page of your resume. The cover letter should address your specific interest in the position and outline skills and experience that directly relate to this position.

Job Summary

Wanted: A meticulous bench scientist who loves organize and manage a laboratory.


  • Do you love meticulous hands-on bench work?
  • Are you attracted to work that requires attention to detail and organization?
  • Are you interested in working closely with a clinical research team?  You’ll work closely with human materials and do research that directly impacts on human outcomes.
  • Are you interested in technology and learning new techniques, such as next-generation sequencing and digital PCR, while also contributing to more routine (yet very important) lab tasks such as developing and maintaining cell culture systems?
  • Do you enjoy the experimental process and the challenges of troubleshooting while developing, optimizing, and implementing methods...even when repeating the experiment for the umpteenth time?
  • Are you passionate about being part of a team that is developing new ways to monitor human health and disease?

If so, you may be a great fit as our Research Laboratory Tech Lead! The Department of Internal Medicine, Division of Hematology/Oncology seeks an inspired scientist to support the activities of a cutting-edge research program focused in preventing cancer. Our lab supports many important clinical trials and manages thousands of human samples.  The laboratory is developing 3 dimensional organ culture methods and has historically been a high sensitivity drug and nutrition analysis laboratory.  The laboratory collaborates with other laboratories to perform complex molecular imaging, genomics, transcriptomics, and proteomics research.  We have the capability to perform quantitative PCR and quantitative western blots.

The applicant will work closely with the PI, graduate students, postdocs, and other research staff in an interdisciplinary translational research laboratory. Final salary and title will be determined by candidate’s experience.


  • Prepare solutions, aliquots, and general lab reagents
  • Provide technical and general lab maintenance and support to enable the laboratory to function effectively
  • Maintain accurate and organized records of experiments, data, and specimens, including organizing specimens, lab reagents, and equipment in databases
  • Responsible for completing lab documentation for safety inspections
  • Separate cellular and non-cellular components from human biofluid and stool specimens, with subsequent RNA extraction and analysis
  • Prepare cDNA libraries from ultra-low input RNA samples using challenging custom protocols and perform next-generation sequencing using the Illumina MiSeq platform
  • Performs advanced literature searches and can analyze content to ensure quality of search.
  • Assists in preparation of research papers, manuscripts, progress reports.
  • Assists the principal investigator in development of research goals.  Decision making responsibility for a substantial portion of project work.
  • Create and maintain 3 dimensional primary human organoids from human samples.


Required Qualifications*

  • Bachelor’s degree and 2-3 years’ experience in a laboratory setting. Basic laboratory skills, including prior bench research experience (minimum 2 years; more preferred).
  • Experience with nucleic acid analysis methods and technologies
  • Will happily process and analyze blood, urine, stool, and other human tissue or biofluid specimens
  • Exceptional organizational skills, including detailed record-keeping
  • Ability to work effectively independently and as part of a team
  • At least 2 first or second author publications
  • Experience with UM IRBMed and UCUCA
  • Some weekend work will be required
  • Knowledge of UM policies and procedures, OSEH training for lab safety, autoclaves, and other relevant training completed.



Background Screening

Michigan Medicine conducts background screening and pre-employment drug testing on job candidates upon acceptance of a contingent job offer and may use a third party administrator to conduct background screenings.  Background screenings are performed in compliance with the Fair Credit Report Act.

Mission Statement

Michigan Medicine improves the health of patients, populations and communities through excellence in education, patient care, community service, research and technology development, and through leadership activities in Michigan, nationally and internationally.  Our mission is guided by our Strategic Principles and has three critical components; patient care, education and research that together enhance our contribution to society.

Application Deadline

Job openings are posted for a minimum of seven calendar days. This job may be removed from posting boards and filled anytime after the minimum posting period has ended.

U-M EEO/AA Statement

The University of Michigan is an equal opportunity/affirmative action employer.