The human immunodeficiency virus (HIV) causes a lethal syndrome (acquired immunodeficiency syndrome) characterized by CD4+ T cell depletion and resultant immunodeficiency. HIV has caused a worldwide epidemic that has killed millions of people and continues to infect about 40,000 people each year in this country. The long-term goal of our research program is to provide improved treatments for people withHIV/AIDS. Existing therapies are highly effective at rendering viral particles non-infectious and thus reducing viral loads. However none of the current drugs are capable of destroying infected cells. Many infected cells have short half-lives and die within days or months. Others, however, remain in a state that is resistant to the immune system and can persist for years. To provide better therapies, our focus has been on understanding the molecular mechanisms of viral persistence within cellular reservoirs. The development of drugs that will inhibit these pathways will bring us closer to a cure.
More information on Dr. Collins lab can be found here: https://collins.lab.medicine.umich.edu
Michigan Medicine improves the health of patients, populations and communities through excellence in education, patient care, community service, research and technology development, and through leadership activities in Michigan, nationally and internationally. Our mission is guided by our Strategic Principles and has three critical components; patient care, education and research that together enhance our contribution to society.
- Perform research either independently or supervised, providing data for manuscripts and grants
- Analyze complex data using statistical approaches to identify significant differences
- Analyze and present journal articles at lab meeting
- Edit, write and/or review manuscripts and grants
- Depending on stage and productivity there will be opportunities to participate in assembling manuscripts and attending national meetings
- Assist graduate students and postdoctoral fellows with routine lab procedures such as plasmid preps, cell purification and flow cytometry
- Purchase lab supplies/stocking and organizing lab
- Maintain lab equipment
- Make solutions and buffers
Bachelor's degree required. Experience with cell culture is needed. Experience with viral vectors including retroviral vectors, nucleic acid extraction and PCR is beneficial. A strong interest in and commitment to advancing our understanding of viral disease pathogenesis is essential.
- Intermediate Level: Bachelor's degree in science and 2-3 years experience required.
- Associate Level: Bachelor's degree in science and minimum one year of experience required.
This position may be underfilled at a lower classification depending on the qualifications of the selected candidate.
Michigan Medicine conducts background screening and pre-employment drug testing on job candidates upon acceptance of a contingent job offer and may use a third party administrator to conduct background screenings. Background screenings are performed in compliance with the Fair Credit Report Act. Pre-employment drug testing applies to all selected candidates, including new or additional faculty and staff appointments, as well as transfers from other U-M campuses.
Job openings are posted for a minimum of seven calendar days. The review and selection process may begin as early as the eighth day after posting. This opening may be removed from posting boards and filled anytime after the minimum posting period has ended.
U-M EEO/AA Statement
The University of Michigan is an equal opportunity/affirmative action employer.