An exciting opportunity has been created for an experienced researcher to join the Shureiqi's Laboratory that is moving from University of Texas/MD to the U of M Division of Heme-Onc and the Rogel Cancer Center in Ann Arbor, MI. This individual will join as a Lab Manager and work directly with Dr. Shureiqi. He/she will be an integral member of research team whose focus is studying molecular targeting of lipid signaling in colorectal cancer tumorigenesis.
Our laboratory focuses on identifying molecular targeting mechanisms of lipid signaling, particularly 15-lipoxgyensase-1 and PPR-delta, to suppress gastrointestinal tumorigenesis especially colon cancer. We use DNA, epigenetic, protein function, immune phenotyping and lipidomic studies in colorectal cancer clinical samples, organoids, genetically modified mouse and cancer cell line model systems to study these mechanisms. Our goal is to develop new, targeted treatment strategies for the prevention and treatment of gastrointestinal cancers especially colorectal cancer.
This individual will be responsible for managing laboratory operations, including regulatory aspects such as IBC, IACUC, and IRB; equipment maintenance and service contracts; ordering supplies and inventorying. Essential job functions also include supervising and carrying out experiments in the laboratory, including: managing genetically modified mouse colonies, mouse xenograft experiments and drug treatment, protein and RNA expression and purification from mammalian cells and bacteria, QPCR, Western blotting, reporter gene analysis, ELISA, tissue culture of mammalian cell lines and transfection.
Michigan Medicine improves the health of patients, populations and communities through excellence in education, patient care, community service, research and technology development, and through leadership activities in Michigan, nationally and internationally. Our mission is guided by our Strategic Principles and has three critical components; patient care, education and research that together enhance our contribution to society.
Why Join Michigan Medicine?
Michigan Medicine is one of the largest health care complexes in the world and has been the site of many groundbreaking medical and technological advancements since the opening of the U-M Medical School in 1850. Michigan Medicine is comprised of over 30,000 employees and our vision is to attract, inspire, and develop outstanding people in medicine, sciences, and healthcare to become one of the world’s most distinguished academic health systems. In some way, great or small, every person here helps to advance this world-class institution. Work at Michigan Medicine and become a victor for the greater good.
What Benefits can you Look Forward to?
- Excellent medical, dental and vision coverage effective on your very first day
- Retirement Savings Opportunities
Performs and supervise other lab members in performing cell culture, molecular biology techniques including: DNA/RNA/protein extraction, QPCR, and Western blots, etc. Management of genetic mouse colonies and perform xenograft tumor growth experiments, drug injections, drug gavage, tumor measurements.
Manages day to day lab operations to include lab orders and stock lab supplies, maintains equipment and submission and maintenance of regulatory approvals (IACUC, IRB, IBC) related to our projects and equipment maintenance.
Assist with grant and manuscript writing and editing.
Additional laboratory duties as assigned by PI
Bachelor’s degree and 4-5 years of experience
Michigan Medicine conducts background screening and pre-employment drug testing on job candidates upon acceptance of a contingent job offer and may use a third party administrator to conduct background screenings. Background screenings are performed in compliance with the Fair Credit Report Act. Pre-employment drug testing applies to all selected candidates, including new or additional faculty and staff appointments, as well as transfers from other U-M campuses.
Job openings are posted for a minimum of seven calendar days. The review and selection process may begin as early as the eighth day after posting. This opening may be removed from posting boards and filled anytime after the minimum posting period has ended.
U-M EEO/AA Statement
The University of Michigan is an equal opportunity/affirmative action employer.