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A cover letter is required for consideration for this position and should be attached as the first page of your resume. The cover letter should address your specific interest in the position and outline skills and experience that directly relate to this position.

Job Summary

The UM Bioinformatics Core is looking for a Bioinformatics Analyst to identify, analyze, and interpret patterns in DNA/RNA from next-generation sequencing (NGS) data.

The Bioinformatics Core is one of the Biomedical Research Core Facilities (BRCF) in Michigan Medicine’s Office of Research; it is a centralized resource that performs data analysis on a fee-for-service basis across diverse areas of biomedical science, serving the analysis needs of both UM researchers and researchers outside of UM. A main focus of the Core is on bulk and single-cell analysis of NGS data (e.g. RNA-seq, Exome-seq, ATAC-Seq, etc.), though we provide a full range of related analyses (e.g. enrichment testing, network/pathways analysis, microarray data analysis) as well as custom bioinformatics analyses as required by Core customers. Effective customer service is critical to the success of the analyst and the Core.


The Bioinformatics Analyst will provide professional analysis services to recharge customers and potentially embed with individual research labs for more intensive collaborations. Bioinformatics is a highly dynamic field and the work will involve a) operation of well-developed and automated tools, b) testing, improvement, and implementation of tools, and c) custom analyses that require novel algorithm/tool development and integration. In addition, the Analyst will:

  • Discuss, advise, and explain experimental/analytical design and analysis results with Core customers.
  • Work closely with collaborating departments and other BRCF Cores to assess new technologies and their potential impacts on data analysis and services.
  • Identify potential anomalies in inputs and/or results and work to resolve any quality issues.
  • Work with the Core project manager to create and estimate project plans. Prepare presentations, reports, and publications to communicate approaches and results to researchers and peers.
  • Operate independently when appropriate and collaborate effectively with researchers and Core team. Regularly participate in scheduled and ad-hoc remote meetings.
  • Document code and analysis methods.
  • Continually update knowledge and skills in the field to remain at the forefront of bioinformatics research.

Required Qualifications*

  • An MS plus three years of experience in an appropriate field emphasizing both computational skills and biological expertise (e.g. Computational Biology, Computer Science, Bioinformatics, Statistical Genetics).
  • Experience analyzing high-throughput data on bulk and/or single-cell experiments. Familiarity with a range of publicly available bioinformatics resources, file formats, and tools (e.g. NCBI/EMBL databases, BED files, Bioconductor)
  • Proficiency with Linux as well as one or more scripting/programming languages (e.g. Python, Perl, R, Java, C).
  • Excellent written and verbal communication skills, effective interpersonal skills, and a drive to excel.
  • Commitment to growing supportive, collaborative relationships within the team and the UM research community.

Desired Qualifications*

  • A PhD or equivalent experience in an appropriate field (see above).
  • Experience with a subset of cancer biology, metagenomics/microbiome data, or single-cell analysis.
  • Enthusiasm for building reproducible scientific workflows (using combination of Docker, Conda, Jupyter, R Markdown, etc.)
  • Familiarity with proprietary genomic tools/resources (e.g. VarSeq, IPA, Genomatix, iPathwayGuide).
  • Laboratory research experience in a life science domain.
  • Customer service experience.

Additional Information

Michigan Medicine values a culture of diversity, equity, and inclusion. Here at Biomedical Research Core Facilities (BRCF), our dedication to customer service is inseparable from our commitment to diversity, equity and inclusion. It is central to our mission as an institutional resource to ensure that each member of our community has full opportunity to thrive in our environment, for we believe that diversity is key to individual flourishing, educational excellence and the advancement of knowledge.

Background Screening

Michigan Medicine conducts background screening and pre-employment drug testing on job candidates upon acceptance of a contingent job offer and may use a third party administrator to conduct background screenings.  Background screenings are performed in compliance with the Fair Credit Report Act. Pre-employment drug testing applies to all selected candidates, including new or additional faculty and staff appointments, as well as transfers from other U-M campuses.

Application Deadline

Job openings are posted for a minimum of seven calendar days.  The review and selection process may begin as early as the eighth day after posting. This opening may be removed from posting boards and filled anytime after the minimum posting period has ended.

U-M EEO/AA Statement

The University of Michigan is an equal opportunity/affirmative action employer.