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Job Summary

The research lab of Dr. Michael Holinstat in the Department of Pharmacology at the University of Michigan, Ann Arbor, MI is in search of a Research Laboratory Specialist Senior. As the selected candidate you will utilize a number of in vivo animal microscopy techniques to investigate platelet activation and real-time regulation of blood clotting, hemostasis, and thrombosis in a number of arterial and venous injury conditions. You will be afforded the ability to work in an open-lab environment with access to all of its state-of-the-art equipment including both an in vivo intravital confocal microscope and an in vivo intravital fluorescent microscope in order to gain a greater understanding of hemostasis and thrombosis in the in vivo, setting in small animal models.

The lab maintains state-of-the-art hemostasis and thrombosis facilities including lumi-aggregometers, flow cytometers, hemavet, a microscopy facility containing 2 zeiss microscopes with the capacity for in vivo intravital confocal microscopy and single-cell high resolution microscopy, PCR machines, 2 multi-mode plate readers, and a phlebotomy suite with full-time phlebotomist. The lab is situated in the heart of Michigan Medicine within steps of a multitude of research resources and easy access to collaborators, the clinics, and animal facilities.

Mission Statement

Michigan Medicine improves the health of patients, populations and communities through excellence in education, patient care, community service, research and technology development, and through leadership activities in Michigan, nationally and internationally.  Our mission is guided by our Strategic Principles and has three critical components; patient care, education and research that together enhance our contribution to society.

Why Join Michigan Medicine?

Michigan Medicine is one of the largest health care complexes in the world and has been the site of many groundbreaking medical and technological advancements since the opening of the U-M Medical School in 1850. Michigan Medicine is comprised of over 30,000 employees and our vision is to attract, inspire, and develop outstanding people in medicine, sciences, and healthcare to become one of the world’s most distinguished academic health systems.  In some way, great or small, every person here helps to advance this world-class institution. Work at Michigan Medicine and become a victor for the greater good.

What Benefits can you Look Forward to?

  • Excellent medical, dental and vision coverage effective on your very first day
  • Retirement Savings Opportunities

Responsibilities*

This position is for an experienced research specialist to work on preclinical and translational research projects focuses on thrombosis and hemostasis.  The lab functions in a collaborative work environment with access to all of the state-of-the-art equipment in order to gain a greater understanding of signaling in the platelet, hemostasis and thrombosis in the in vitro, ex vivo, and in vivo setting in both human and mouse models.  As the selected candidate your essential function will be to perform the day-to-day-operation of using intravital fluorescent microscopy to study blood vessel function and clotting, as well as, designing and executing laboratory experiments, and applying standard scientific protocols to experiments and research.

Required Qualifications*

  • A PhD in pharmacology, physiology, biochemistry, molecular biology, or other related biomedical discipline
  • A minimum of 5 years of laboratory experience working with microvascular surgical techniques in mouse models
  • Experience working with small animals
  • Digital image acquisition involving real-time in vivo assays and analysis and interpretation of data

In order to be considered for this position, the applicant must have met or will have met all the required qualifications prior to the start date of employment.

Desired Qualifications*

  • Experience in intravital microscopy looking at vessel hemostasis and thrombosis in the mouse model
  • Experience with flow cytometry, western blot techniques, and working in a team environment
  • An understanding of lipid biology, protein chemistry, biochemistry, pharmacology, and signal transduction

Background Screening

Michigan Medicine conducts background screening and pre-employment drug testing on job candidates upon acceptance of a contingent job offer and may use a third party administrator to conduct background screenings.  Background screenings are performed in compliance with the Fair Credit Report Act. Pre-employment drug testing applies to all selected candidates, including new or additional faculty and staff appointments, as well as transfers from other U-M campuses.

Application Deadline

Job openings are posted for a minimum of seven calendar days.  The review and selection process may begin as early as the eighth day after posting. This opening may be removed from posting boards and filled anytime after the minimum posting period has ended.

U-M EEO/AA Statement

The University of Michigan is an equal opportunity/affirmative action employer.