The Department of Emergency Medicine is seeking a highly motivated Research Technician to join the Greineder lab. Our lab studies targeted drug delivery and translational drug design. The overarching goal is to develop novel therapeutic and technologies for emergent diseases that don't currently have great treatment options. As an Emergency Medicine lab, our focus is less on one specific disease or organ system and more on what the specific pharmacologic needs are for each disease. As a technician, this means exposure to a wide range of exciting projects and applications -- currently, we are working on a bispecific antibody that crosses the blood brain barrier and protects neurons from stroke, cardiac arrest, and TBI, a fusion protein therapeutic for an untreatable form of hemolytic anemia, a nanoparticle to target brain cancer and others. In each case, the techniques required as a technician are the same: molecular biology to clone and assemble the targeting ligands and therapeutic cargo, protein production in bacteria or mammalian cells, affinity chromatography for purification, and HPLC for QC and, occasionally, bioconjugation. We test our novel agents in animals and, in some cases, realistic models of human disease, with an eye towards the creation of new intellectual property and translation to the clinic. The lab environment is highly collaborative and all contributions are honored with co-authorship. Those looking to do real drug design and translational pharmacology are encouraged to apply.
Michigan Medicine improves the health of patients, populations and communities through excellence in education, patient care, community service, research and technology development, and through leadership activities in Michigan, nationally and internationally. Our mission is guided by our Strategic Principles and has three critical components; patient care, education and research that together enhance our contribution to society.
Primary responsibilities will be planning and conducting bench experiments and meticulous documentation. Analysis of data, typically with the assistance of the PI, will also be expected. The technician will have some responsibilities for lab maintenance -- e.g. participating in lab safety self-inspections, identifying/ordering supplies and key reagents, etc.
Bachelor’s degree and past employment or work experience of no less than 1 years as a full time research technician working in molecular biology. A strong foundation in math (ability to calculate dilutions, familiarity with scientific notation, etc) is a must. The successful candidate will have a strong work ethic, collaborative attitude, and excellent organizational and time management skills. Must be enthusiastic about developing new expertise and taking some degree of ownership over a project or projects within the lab.
Bachelors’s degree in molecular biology, biochemistry, biology, engineering (e.g., BME, ChemE) or related scientific degree, with 2 or more years of experience in laboratory research. Previous experience with molecular biology (cloning), mammalian or insect cell culture, protein production and/or purification, flow cytometry, microscopy, HPLC, handling of lab animals, and animal surgery are all preferred. The successful candidate will own projects based on previous experience and expertise. Prior supervision of less-experienced students and technicians is desired.
Full time Monday through Friday. Flexible schedule preferred.
The Department of Emergency Medicine at Michigan Medicine is committed to creating an environment that is welcoming to all. We strive to value the unique contributions of individuals, and support a culture of inclusivity among our employees, learners and larger community. This includes supporting the development of a diverse workforce across identities such as the race, ethnicity, national origin, sexual orientation, gender identity, age, citizenship, marital status, religion, language, disability, and Veteran status. We are proud to be an equal opportunity and an affirmative action employer
Michigan Medicine conducts background screening and pre-employment drug testing on job candidates upon acceptance of a contingent job offer and may use a third party administrator to conduct background screenings. Background screenings are performed in compliance with the Fair Credit Report Act. Pre-employment drug testing applies to all selected candidates, including new or additional faculty and staff appointments, as well as transfers from other U-M campuses.
Job openings are posted for a minimum of seven calendar days. The review and selection process may begin as early as the eighth day after posting. This opening may be removed from posting boards and filled anytime after the minimum posting period has ended.
U-M EEO/AA Statement
The University of Michigan is an equal opportunity/affirmative action employer.