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How to Apply

A cover letter is required for consideration for this position and should be attached as the first page of your resume. The cover letter should address your specific interest in the position and outline skills and experience that directly relate to this position.

Job Summary

This position will support collaborative work in the NeuroNetwork for Emerging Therapies that utilizes complementary in vivo and in vitro models to facilitate research discoveries with translational potential for Alzheimer’s disease (AD), as well as amyotrophic lateral sclerosis and neurologic complications of diabetes, obesity, and aging. Specific tasks will include in vivo rodent studies, rodent behavior studies, tissue analyses, in vitro cell culture, gene and protein expression analysis, immunocytochemistry, and immunofluorescence microscopy. The individual will also assist with protocol optimization, study documentation, and basic data analysis and report preparation. Given the critical need for research on neurodegenerative disease treatments and mechanisms, the volume of ongoing laboratory research studies, and the pending departure of an individual currently responsible for these duties for our AD studies, many of which are supported by the NIH or other agencies, an experienced individual with the ability to accurately and efficiently carry out the range of tasks associated with our AD-specific research will be incredible value added for our research team and the organization.

Why Join Michigan Medicine?

Michigan Medicine is one of the largest health care complexes in the world and has been the site of many groundbreaking medical and technological advancements since the opening of the U-M Medical School in 1850. Michigan Medicine is comprised of over 30,000 employees and our vision is to attract, inspire, and develop outstanding people in medicine, sciences, and healthcare to become one of the world’s most distinguished academic health systems.  In some way, great or small, every person here helps to advance this world-class institution. Work at Michigan Medicine and become a victor for the greater good.

What Benefits can you Look Forward to?

  • Excellent medical, dental and vision coverage effective on your very first day

  •  Retirement Savings Opportunities

Responsibilities*

  • Rodent handling and husbandry including administering injections, recording weekly body weights, routine phenotyping, and inputting data into our laboratory’s information management system.

  • Rodent surgery including intracranial and intraspinal stereotaxic injections.

  • In vivo imaging including MRI, CT and BLI.

  • Tissue dissection, collection and processing including OCT and paraffin embedding, sectioning, DNA/RNA isolation.

  • Tissue analysis including ELISA, qPCR, western blotting and immunohistochemistry and advanced imaging, including laser-scanning confocal imaging.

  • Coordination of research activities, project planning and liaising with collaborators and core facilities.

  • Data and statistics analysis using common laboratory computer programs, such as MS Suite, Adobe applications, Metamorph, Imaris, NanoDrop, MATLAB, R and GraphPad Prism.

  • Identification and optimization of novel laboratory techniques, basic data analysis, and report preparation.

  • Train and provide basic laboratory/safety oversight to students and junior laboratory technicians.

  • Other tasks as needed.

Required Qualifications*

  • Bachelor’s degree in Biological Sciences or equivalent.

  • Must have at least 2 years of relevant laboratory experience.

  • Demonstrated experience working with rodents required, along with expertise in related in vivo techniques and assessments (e.g. rodent handling, surgery, injections, behavior testing, in vivo imaging).

  • Experience with histological techniques, cell culture, and in vitro cell-based assays (e.g. tissue dissection, tissue processing, sectioning, immunohistochemistry, qPCR, western blot, ELISA and microscopy).

  • Experience in experimental design and planning.

  • Must be proficient with standard computer software (e.g. MS word, excel, PowerPoint, Adobe Photoshop, Illustrator) and data analysis software (e.g. GraphPad Prism, Metamorph, MATLAB, R) and willing to learn new programs as needed.

  • Organization, attention to detail, punctuality, and flexibility required.

  • Ability to work independently with limited supervision as required.

  • Excellent interpersonal skills and ability to work with others in a collaborative environment.

  • Strong oral and written communication skills.

Desired Qualifications*

  • Background in neuroscience or neurology preferred.

  • Evidence of fine motor skills desired to support necessary cellular and tissue micro-dissection.

  • Experience with stem cell culture and differentiation protocols and flow cytometry preferred.

  • Experience with image analysis techniques and programs preferred.

Background Screening

Michigan Medicine conducts background screening and pre-employment drug testing on job candidates upon acceptance of a contingent job offer and may use a third party administrator to conduct background screenings.  Background screenings are performed in compliance with the Fair Credit Report Act. Pre-employment drug testing applies to all selected candidates, including new or additional faculty and staff appointments, as well as transfers from other U-M campuses.

Application Deadline

Job openings are posted for a minimum of seven calendar days.  The review and selection process may begin as early as the eighth day after posting. This opening may be removed from posting boards and filled anytime after the minimum posting period has ended.

U-M EEO/AA Statement

The University of Michigan is an equal opportunity/affirmative action employer.