The Michele Laboratory is seeking a postdoctoral fellow to study the molecular mechanisms of human muscular dystrophies and cardiomyopathies associated with mutations in the dystrophin-glycoprotein complex and other muscle proteins. This NIH funded research will focus on understanding the mechanisms of muscle membrane stability and muscle membrane repair using physiological measures of injury in whole muscle in vivo, and live cell imaging of membrane repair in isolated muscle fibers and tissue engineered models of striated muscle. The fellow will be provided the opportunity to advance their career through training in state-of-the-art experimental work, exposure to laboratory and project management, development of independent thinking and leadership skills, and other career development opportunities.
What You'll Do
- The fellow will be the primary lead on the project and will execute experimental work focused on live cell injury of muscle membrane repair.
- The fellow will help mentor and supervise undergraduate students in the laboratory that are assisting the project
- The fellow will write their own fellowships and manuscripts, and assist with other grant preparation.
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- M.D., Ph.D., or equivalent degree in a relevant discipline (Biology, Biochemistry, Physiology, etc.).
- A record of authorship in peer-reviewed publications.
- Previous experience in muscle physiology or muscle cell biology
- Experience with animal models of human genetic disease
- Experience in induced pluripotent stem cells
- Experience with confocal or live cell microscopy and imaging
- Previous success in fellowship writing or grant writing
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