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Job Summary

Dr. Espinoza-Fonseca’s laboratory in the Division of Cardiovascular Medicine, Department of Internal Medicine is looking for a postdoctoral fellow with a background in pharmacology, toxicology, cellular biology and animal experimentation.

Dr. Espinoza-Fonseca’s lab is interested in understanding the fundamental molecular motions and interactions that are responsible for regulating calcium transport in muscle cells, and designing effective molecular therapies to treat human diseases associated with dysregulation of calcium transport in the muscle cells.

We are looking for a talented and highly motivated candidate in bench research interested in the mechanisms of calcium dysregulation diseases and development of therapies targeting the heart.  Our lab is working on a diverse array of biological questions, so the specific postdoctoral project will depend on the candidate's interests and expertise.

Mission Statement

Michigan Medicine improves the health of patients, populations and communities through excellence in education, patient care, community service, research and technology development, and through leadership activities in Michigan, nationally and internationally.  Our mission is guided by our Strategic Principles and has three critical components; patient care, education and research that together enhance our contribution to society.

Responsibilities*

Perform experiments and assays related to designing effective molecular therapies to treat human diseases associated with dysregulation of calcium transport in the muscle cells. These include but are not limited to the following: mammalian cell culture; microscopy; protein production in cell-based systems; protein extraction, purification and quantification; enzymatic activity assays; recombinant DNA production; immunoblotting, quantitative RT-PCR; and animal handling. Troubleshoot problems and recommend solutions. Evaluate experiment results using statistical and multivariate analysis.

Assist the PI with proposal and manuscript writing.

Required Qualifications*

  • PhD in cell biology, pharmacology, physiology, toxicology and related areas.
  • Experience in cardiac physiology and pharmacology.
  • Excellent written and oral communication skills.
  • This individual must be self-motivated and perform well under pressure as well as without set deadlines. This individual must be meticulously organized and detail oriented.

Desired Qualifications*

  • Experience with standard molecular biology work, including DNA/RNA extraction, PCR, cloning, plasmid generation, etc.
  • Experience with human induced pluripotent stem cell differentiation into cardiac myocytes.
  • Experience with myocyte cell isolation.

Background Screening

Michigan Medicine conducts background screening and pre-employment drug testing on job candidates upon acceptance of a contingent job offer and may use a third party administrator to conduct background screenings.  Background screenings are performed in compliance with the Fair Credit Report Act. Pre-employment drug testing applies to all selected candidates, including new or additional faculty and staff appointments, as well as transfers from other U-M campuses.

Application Deadline

Job openings are posted for a minimum of seven calendar days.  The review and selection process may begin as early as the eighth day after posting. This opening may be removed from posting boards and filled anytime after the minimum posting period has ended.

U-M EEO/AA Statement

The University of Michigan is an equal opportunity/affirmative action employer.