Join the expanding Michigan Center for Translational Pathology laboratory to work in the cancer genomics research team. Our CLIA certified laboratory uses high-throughput technologies to understand the mechanisms of cancer progression, and to develop new prognostic/diagnostic biomarkers of cancer. The laboratory provides enormous resources and opportunities for an individual to learn traditional cellular/molecular techniques, as well as state-of-the-art technologies, including Next Generation Sequencing for genomes, transcriptomes, and epigenomes. The candidate will work primarily with a group of senior laboratory personnel to assist and collaborate with researchers within the laboratory and beyond.
Michigan Medicine improves the health of patients, populations and communities through excellence in education, patient care, community service, research and technology development, and through leadership activities in Michigan, nationally and internationally. Our mission is guided by our Strategic Principles and has three critical components; patient care, education and research that together enhance our contribution to society.
Detailed duties include: Performing molecular and cellular experiments on the mechanisms of cancer progression and therapy resistance, particularly in prostate, breast, myeloma, and rare cancers. Experiments will include molecular cloning of genetic aberrations identified through next-generation sequencing followed by expression and establishment of cell culture model systems. CRISPR technologies will be used to establish knockout and conditional knockout models. The applicant will learn how to generate next-generation sequencing libraries spanning a range of technologies, from cell-free DNA to ChIP-Seq.
This position is ideal for individuals who are interested in leading projects. The work has the potential to lead to discoveries that can directly translate into the clinic. This position will also co-ordinate research projects with other staff and undergraduate students.
- Master’s degree in biology and genetics.
- A minimum of 5 years’ experience in molecular biology research laboratory.
- Proficiency with PCR techniques, and molecular cloning.
- Proficiency with cell culture techniques, including transfection and selection of clones.
- Proficiency in Western blotting and other methods of protein analysis.
- Expert on virus transduction to cell lines, including primary cell.
- Extensive experiences on UM EHS, lab safety, and lab general management, teach and supervise students.
- Willingness to learn new concepts and technologies.
- Demonstrated ability to work with others in a collaborative environment.
- Strong organization skills, attention to details, very good record keeping skills, and must be able to complete work in a timely manner.
Michigan Medicine conducts background screening and pre-employment drug testing on job candidates upon acceptance of a contingent job offer and may use a third party administrator to conduct background screenings. Background screenings are performed in compliance with the Fair Credit Report Act. Pre-employment drug testing applies to all selected candidates, including new or additional faculty and staff appointments, as well as transfers from other U-M campuses.
Job openings are posted for a minimum of seven calendar days. The review and selection process may begin as early as the eighth day after posting. This opening may be removed from posting boards and filled anytime after the minimum posting period has ended.
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The University of Michigan is an equal opportunity/affirmative action employer.
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COVID-19 vaccinations are now required for all University of Michigan students, faculty and staff across all three campuses, including Michigan Medicine, by the start of the fall term on August 30, 2021. This includes those working or learning remotely. More information on this policy is available on the Campus Blueprint website or the U-M Dearborn and U-M Flint websites.