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How to Apply

A cover letter is required for consideration for this position and should be attached as the first page of your resume. The cover letter should address your specific interest in the position and outline skills and experience that directly relate to this position.

Job Summary

The Michigan Center for Translational Pathology (MCTP) is looking for a Research Lab Specialist Associate to serve as an integral member of its In Vivo Group. The MCTP is a large multidisciplinary institute in which sequencing and bioinformatics analysis drives discovery of novel cancer-related genes. The In Vivo group mechanistically evaluates promising targets and tests novel cancer therapies in mouse, cell and human tissue-based models. The position requires an individual comfortable working independently and as part of a team to perform the duties listed below.

Mission Statement

Michigan Medicine improves the health of patients, populations and communities through excellence in education, patient care, community service, research and technology development, and through leadership activities in Michigan, nationally and internationally.  Our mission is guided by our Strategic Principles and has three critical components; patient care, education and research that together enhance our contribution to society.

Responsibilities*

  • Maintenance of a transgenic mouse colony. 
  • Tumor xenografting via subcutaneous, intraperitoneal, renal capsule, and orthotopic placement. 
  • Tumor growth monitoring by caliper measurement or imaging. 
  • Pre-operative preparation and performance of aseptic surgery, including orchiectomy. 
  • Administration of therapeutic drugs via subcutaneous, intraperitoneal, IV, and oral gavage delivery. 
  • Mouse necropsy and histological tissue processing (paraffin embedding/ sectioning).  
  • Cell culture (IC50, xenograft preparation, tumor organoid models).
  • DNA/ RNA isolation, PCR.
  • Protein isolation, Western blot.
  • Record keeping, including animal inventory, experimental procedure logs, protocols/ SOPs.
  • Management of animal protocol in eRAM.
  • Basic lab management/ EHS compliance.

Required Qualifications*

  • Bachelor’s degree or higher with specialization in cell biology or a related field. 
  • At least 2 years’ biology lab experience. 
  • Experience in cell culture, DNA/RNA/protein isolation, PCR genotyping, qPCR, Western blotting.
  • Basic mouse handling experience.
  • Ability to work in an environment in which one is exposed to animals/ animal dander.
  • Knowledge and understanding of laboratory safety and ability to work carefully with potentially harmful agents.

Desired Qualifications*

  • Willing to have some schedule flexibility (and occasionally work on weekends)
  • Cell culture experience
  • Molecular biology experience (cloning, etc)
  • Mouse colony management experience
  • Experience with animal protocol management in eRAM

Work Schedule

M-F, 8:00-5:00

Work Locations

Rogel Cancer Center

Background Screening

Michigan Medicine conducts background screening and pre-employment drug testing on job candidates upon acceptance of a contingent job offer and may use a third party administrator to conduct background screenings.  Background screenings are performed in compliance with the Fair Credit Report Act. Pre-employment drug testing applies to all selected candidates, including new or additional faculty and staff appointments, as well as transfers from other U-M campuses.

Application Deadline

Job openings are posted for a minimum of seven calendar days.  The review and selection process may begin as early as the eighth day after posting. This opening may be removed from posting boards and filled anytime after the minimum posting period has ended.

U-M EEO/AA Statement

The University of Michigan is an equal opportunity/affirmative action employer.

 

U-M COVID-19 Vaccination Policy

COVID-19 vaccinations are now required for all University of Michigan students, faculty and staff across all three campuses, including Michigan Medicine.  This includes those working or learning remotely.  More information on this policy is available on the Campus Blueprint website or the U-M Dearborn and U-M Flint websites.