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How to Apply

Interested applicants should submit a brief statement of interest, CV, and contact information for three references. For questions regarding the position, please contact Dr. Joshua Welch at


The Welch Laboratory at the University of Michigan is seeking a postdoctoral researcher to develop and apply algorithms, machine learning methods, and statistical models for analysis of single-cell genomic data. Our research focuses on enabling biological discovery by applying novel computational approaches to genomic data. Broadly, we seek to understand what genes define the complement of cell types and cell states within healthy tissue, how cells differentiate to their final fates, and how dysregulation of genes within specific cell types contributes to human disease. The lab publishes in high-impact journals, including Cell, Nature, and Nature Biotechnology.

This postdoctoral position will focus on methods for analyzing and integrating single-cell RNA-seq, single-cell epigenome data, and spatial transcriptomic data as part of several NIH-funded-projects. We have data and biological collaborators from several different systems, including mouse bone, mouse brain, and human hematopoietic stem cells. This is such an exciting and fast-moving field that Nature Methods recently selected "Single-Cell Multimodal Omics Analysis" as the Method of the Year 2019 and "Spatial Resolved Transcriptomics" as the Method of the Year 2020.

A unique benefit of this position is the rich set of collaborative opportunities available, allowing truly interdisciplinary training. Our collaborative network includes bench scientists and computational method development colleagues within the Single-Cell Spatial Analysis Program, the Michigan Neuroscience Institute, and the Michigan Institute for Data Sciences (MIDAS). Additional opportunities for collaboration are available with faculty in the Artificial Intelligence Laboratory in the Department of Computer Science and Engineering. 

Mission Statement

Michigan Medicine improves the health of patients, populations and communities through excellence in education, patient care, community service, research and technology development, and through leadership activities in Michigan, nationally and internationally.  Our mission is guided by our Strategic Principles and has three critical components; patient care, education and research that together enhance our contribution to society.

Required Qualifications*

  • A PhD in computational biology, bioinformatics, computer science, statistics, mathematics, physics, or related field, and familiarity with high-throughput sequencing data.

Life scientists with significant computational expertise should also apply.

Desired Qualifications*

Additional desirable qualities include the ability to effectively work both independently and in a team, good communication skills, and a love for both computational method development and biological discovery.

Background Screening

Michigan Medicine conducts background screening and pre-employment drug testing on job candidates upon acceptance of a contingent job offer and may use a third party administrator to conduct background screenings.  Background screenings are performed in compliance with the Fair Credit Report Act. Pre-employment drug testing applies to all selected candidates, including new or additional faculty and staff appointments, as well as transfers from other U-M campuses.

Application Deadline

Job openings are posted for a minimum of seven calendar days.  The review and selection process may begin as early as the eighth day after posting. This opening may be removed from posting boards and filled anytime after the minimum posting period has ended.

Vaccine Requirements

COVID-19 vaccinations are required for all students, faculty and staff working in the following areas: Michigan Medicine including the Medical School, Dental School, University Health Service or the Mary A. Rackham Institute.  This includes those working remotely and temporary workers.   More information on this new policy is available on the U-M Health Response.

U-M EEO/AA Statement

The University of Michigan is an equal opportunity/affirmative action employer.