How to Apply
A cover letter is required for consideration of the position and should be attached as the first page of your resume. The cover letter should address your specific interest in the position and outline skills and experience that directly relate to this position.
A research position is available at the University of Michigan in the Muscle Biology Laboratory (https://www.kines.umich.edu/research/mbl) to identify the mechanisms whereby exercise and/or dietary modifications improve insulin signaling and insulin-stimulated glucose uptake in rodent skeletal muscle. The successful applicant will provide entry-level technical support for research on this topic in the Muscle Biology Laboratory. The successful applicant will be working under the guidance of the PI and and other experienced research staff. The goal is to use physiological, biochemical, molecular and cellular approaches to test specific hypotheses about the mechanisms accounting for exercise and diet effects on signaling and glucose uptake in rat muscle.
The individual will be responsible for participating discrete components of a larger research project. S/he will work with the PI and other lab staff to conduct, often in collaboration with other lab members. The individual will be assisting in the treatment of research animals (rats) including diet and exercise protocols, and will be performing analysis of biological samples (rat skeletal muscle and other tissues). Laboratory procedures will include, but not be limited to, diet and/or exercise treatments with rats, assisting with ex vivo incubation of tissues, tissue sample processing, western blotting, spectrophotometric protein assays, dissection and quantification of single muscle fiber characteristics, and glucose uptake assays using radioisotopes. The individual will assist in physiological experiments with rats. S/he will need to be able to work with the PI and other lab members to perform methods and procedures, as needed. S/he will need to maintain research databases and perform basic statistical analyses of data. Must be willing to occasionally work on weekends.
The items below summarize the approximate amount of time for various responsibilities for this position.
27.5% - Assisting with research animal (rat) treatment and care, including providing food, monitoring animal recovery after minor surgeries, monitoring animals during exercise protocols, injecting animals with anesthetic, assisting with tissue dissections.
27.5% - Assisting with ex vivo tissue incubation procedures: transferring tissues (muscles) into vials containing solutions and radioisotopes (3H and/or 14C), freezing muscles after completion of incubation, organizing and storing biological samples.
15% - Processing tissue samples: weighing samples, homogenizing samples, centrifuging and solubilizing samples, pipetting samples.
15% - Biological and biochemical analyses: making solutions, performing spectrophotometric assays (e.g., for protein concentration), performing SDS polyacrylamide gel electrophoresis, performing western blotting, image quantitation using image analysis software.
10% - Lab organization, cleaning, etc.: cleaning glassware, cleaning laboratory, organizing supplies, picking up supplies from the loading dock or order receiving location in the building, working with others (including research staff and students).
5% - Data management and analysis: assisting with data entry, performing statistical analysis using statistical software, assisting with making figures, attending and participating in lab meetings.
The individual should have a B.S. degree or equivalent in a biological science (including Movement Science or Exercise Science) including successful completion of college coursework with biological and/or chemical laboratory sections. Experience working as an employee or volunteer in a biological research laboratory is highly desirable. The candidate must be honest, dependable, and highly motivated. The potential for technical skill in the lab is necessary. Willingness and ability to perform research using rodent research models is required. Willingness to perform research using radioisotopes (3H and 14C) is required. S/he must be willing and able to learn new methods as needed. The ability to work effectively as part of research team is essential. The successful candidate will be able to work under supervision as a member of a research team.
Experience and proficiency in research with rodents is preferred.
This is a 1-year term limited position with the potential to extend based on funding and success in the role. The general salary range for this position is $31-36K. An offer may be extended outside of this range based on equity, experience, knowledge, and skills for the position. You are encouraged to discuss salary questions to honor understanding and transparency throughout the recruiting process. Benefits are included with this position.
The University of Michigan conducts background checks on all job candidates upon acceptance of a contingent offer and may use a third party administrator to conduct background checks. Background checks will be performed in compliance with the Fair Credit Reporting Act.
This position may be underfilled at a lower classification depending on the qualifications of the selected candidate.
Job openings are posted for a minimum of seven calendar days. The review and selection process may begin as early as the eighth day after posting. This opening may be removed from posting boards and filled anytime after the minimum posting period has ended.
U-M EEO/AA Statement
The University of Michigan is an equal opportunity/affirmative action employer.
U-M COVID-19 Vaccination Policy
COVID-19 vaccinations, including one booster when eligible, are required for all University of Michigan students, faculty and staff across all campuses, including Michigan Medicine. This includes those working remotely and temporary workers. More information on this new policy is available on the U-M Health Response website or the UM-Dearborn and UM-Flint websites.