Summary
The Ganesh lab is seeking talented Postdoctoral Research Fellow candidates for human genetics studies of cardiovascular disease. This is an ideal position for a trainee with a computational background who is seeking experience and skills in the application of genetic analysis methods to understand human disease.
We are conducting gene discovery studies using genome sequencing, GWAS and transcript expression profiling methods to understand both common and rare vascular diseases. We are generating epigenetic data sets for integrative genomic studies. In the wet lab side of the laboratory, we use in vitro cellular and in vivo models to assess the functional significance of our genomic discoveries. This will provide an opportunity for collaboration with functionally oriented lab personnel and trainees. Our studies are closely tied to the clinic, with human tissue and blood samples from meticulously phenotyped patients and thus candidates can expect to gain exposure to translational aspects of their research projects as well. This is an opportunity to join a dynamic laboratory that is using genetic and genomic discovery approaches to study novel influences on disease, using both dry-lab and wet-lab approaches.
This position will emphasize approaches to study rare and polygenic variation contributing to disease risk as well as sequencing data analysis. We have several data sets and reagents already generated (exome sequencing, GWAS genotyping, cellular and mouse models) that provide a rich opportunity for productivity and publications for a highly motivated postdoctoral fellow.
The laboratory has secured multiple NIH and non-NIH sources of funding. Dr. Ganesh is a faculty mentor of several NIH-supported T32 training grants at University of Michigan. There is a current opportunity for NIH training grant support and if interested, please get in touch soon to discuss.
Mission Statement
Michigan Medicine improves the health of patients, populations and communities through excellence in education, patient care, community service, research and technology development, and through leadership activities in Michigan, nationally and internationally. Our mission is guided by our Strategic Principles and has three critical components; patient care, education and research that together enhance our contribution to society.
Why Join Michigan Medicine?
Michigan Medicine is one of the largest health care complexes in the world and has been the site of many groundbreaking medical and technological advancements since the opening of the U-M Medical School in 1850. Michigan Medicine is comprised of over 30,000 employees and our vision is to attract, inspire, and develop outstanding people in medicine, sciences, and healthcare to become one of the world’s most distinguished academic health systems. In some way, great or small, every person here helps to advance this world-class institution. Work at Michigan Medicine and become a victor for the greater good.
Responsibilities*
Under the guidance of the PI:
- Sequencing data study planning, data quality control, analysis and reporting
- Learn as needed new analysis methods
- Summarize and communicate results
- Apply for grant funding
- Prepare and submit manuscripts
- Maintain regulatory and data permissions
- Participate in regular lab meetings, institutional research meetings and national conferences
Required Qualifications*
- PhD or MD degree
- Experience with genomic data handling and analysis
- Solid understanding of basic human genetics principles
- Candidates should have publications in genomics or molecular genetics fields with an interest in human genetics
- Candidates should have publications in genomics or molecular genetics fields with an interest in human genetics. The ideal candidate is highly motivated to learn solid scientific methods and to write manuscripts and grant applications.
Desired Qualifications*
- Experience with scientific writing
Background Screening
Michigan Medicine conducts background screening and pre-employment drug testing on job candidates upon acceptance of a contingent job offer and may use a third party administrator to conduct background screenings. Background screenings are performed in compliance with the Fair Credit Report Act. Pre-employment drug testing applies to all selected candidates, including new or additional faculty and staff appointments, as well as transfers from other U-M campuses.
Application Deadline
Job openings are posted for a minimum of seven calendar days. The review and selection process may begin as early as the eighth day after posting. This opening may be removed from posting boards and filled anytime after the minimum posting period has ended.
Vaccine Requirements
COVID-19 vaccinations are required for all students, faculty and staff working in the following areas: Michigan Medicine including the Medical School, Dental School, University Health Service or the Mary A. Rackham Institute. This includes those working remotely and temporary workers. More information on this new policy is available on the U-M Health Response.
U-M EEO/AA Statement
The University of Michigan is an equal opportunity/affirmative action employer.