The Ganesh lab is seeking talented Postdoctoral Research Fellow candidates for human genetics studies of cardiovascular disease. This is an ideal position for a trainee with a computational background who is seeking experience and skills in the application of genetic analysis methods to understand human disease.
We are conducting gene discovery studies using genome sequencing, GWAS and transcript expression profiling methods to understand both common and rare vascular diseases. We are generating epigenetic data sets for integrative genomic studies. In the wet lab side of the laboratory, we use in vitro cellular and in vivo models to assess the functional significance of our genomic discoveries. This will provide an opportunity for collaboration with functionally oriented lab personnel and trainees. Our studies are closely tied to the clinic, with human tissue and blood samples from meticulously phenotyped patients and thus candidates can expect to gain exposure to translational aspects of their research projects as well. This is an opportunity to join a dynamic laboratory that is using genetic and genomic discovery approaches to study novel influences on disease, using both dry-lab and wet-lab approaches.
This position will emphasize approaches to study rare and polygenic variation contributing to disease risk as well as sequencing data analysis. We have several data sets and reagents already generated (exome sequencing, GWAS genotyping, cellular and mouse models) that provide a rich opportunity for productivity and publications for a highly motivated postdoctoral fellow.
The laboratory has secured multiple NIH and non-NIH sources of funding. Dr. Ganesh is a faculty mentor of several NIH-supported T32 training grants at University of Michigan. There is a current opportunity for NIH training grant support and if interested, please get in touch soon to discuss.
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Under the guidance of the PI:
- Sequencing data study planning, data quality control, analysis and reporting
- Learn as needed new analysis methods
- Summarize and communicate results
- Apply for grant funding
- Prepare and submit manuscripts
- Maintain regulatory and data permissions
- Participate in regular lab meetings, institutional research meetings and national conferences
- PhD or MD degree
- Experience with genomic data handling and analysis
- Solid understanding of basic human genetics principles
- Candidates should have publications in genomics or molecular genetics fields with an interest in human genetics
- Candidates should have publications in genomics or molecular genetics fields with an interest in human genetics. The ideal candidate is highly motivated to learn solid scientific methods and to write manuscripts and grant applications.
- Experience with scientific writing
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