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A cover letter is required for consideration for this position and should be attached as the first page of your resume. The cover letter should address your specific interest in the position and outline skills and experience that directly relate to this position.


The Kaczorowski lab at the University of Michigan is recruiting post-doctoral scholars to study patch-seq experiments using brain slice electrophysiology to study mice resilient to developing cognitive deficits despite harboring causal mutations (see Neuner et al., 2019, Neuron). The successful candidate will apply cutting-edge technologies including electrophysiology and single-cell RNAseq to study cellular and molecular signatures associated susceptibility and resilience to Alzheimer’s disease, normal cognitive aging, and other neurodegenerative diseases. Well-defined cellular and molecular signatures will be fed into the drug discovery pipeline and/or subjected to CRISPR-screens to identify genetic modifiers of resilience. The Kaczorowski Lab team values excellence, integrity, diversity, impact and kindness - and we are looking for postdoctoral trainees who are enthusiastic, creative and experienced in electrophysiology and single-cell RNAseq.

The Kaczorowski lab is in the Department of Neurology at the University of Michigan Medical School located in Ann Arbor, Michigan. The city is ranked among the top 10 places to live in the U.S, with a community that is culturally rich, diverse, pedestrian and bike friendly. The Michigan Neuroscience Institute (MNI) continues to be a leader in innovative, collaborative, and visionary research in the areas of brain science and brain impacting diseases. MNI’s cross-disciplinary research portfolio reflects the full range of basic and translational projects from molecular analyses to animal models to human applications. More information about the Kaczorowski lab can be found at or on Twitter @KaczorowskiLab.


The successful candidate will be able to plan, develop, execute, and analyze an independent research project in the context of a supportive lab and institutional environment. In addition, they will supervise and help train graduate students, undergraduate research assistants, and junior technicians in the lab. We are looking for someone that has the aptitude to learn new techniques, works well with others, and possesses strong critical thinking skills.
•    Help maintain lab organization and record all information in an official laboratory notebook.
•    Maintain organization of lab protocols, equipment operation and standard techniques.
•    Participate in periodic research discussions.
•    Present data and plans for new experiments during laboratory meetings.
•    Collaborate with colleagues to develop and achieve short- and long-range plans.
•    Assists with the creation of posters, manuscripts, and presentations for scientific meetings and/or grant submissions.
•    Provides other support to the program as directed.

Required Qualifications*

•    Education: Ph.D. in a biological sciences discipline (e.g., neuroscience, molecular biology, pharmacology, cell biology, molecular genetics).

Desired Qualifications*

•    Experience with electrophysiology platforms such as the pClamp suite or Axograph for the acquisition and analysis of electrophysiology data is preferred.
•    Familiarity with the preparation and use of acute mouse brain slices.
•    Strong training background in neuroscience and neurophysiology/anatomy.
•    Other areas of experience/training include cell biology or genetics.
•    Exceptional verbal and written communication skills.
•    Self-motivated and career-oriented individual preferred.
•    Experience with statistical analysis; interprets and evaluates results and compiles data for peer and PI review.

Background Screening

Michigan Medicine conducts background screening and pre-employment drug testing on job candidates upon acceptance of a contingent job offer and may use a third party administrator to conduct background screenings.  Background screenings are performed in compliance with the Fair Credit Report Act. Pre-employment drug testing applies to all selected candidates, including new or additional faculty and staff appointments, as well as transfers from other U-M campuses.

Application Deadline

Job openings are posted for a minimum of seven calendar days.  The review and selection process may begin as early as the eighth day after posting. This opening may be removed from posting boards and filled anytime after the minimum posting period has ended.

Vaccine Requirements

COVID-19 vaccinations are required for all students, faculty and staff working in the following areas: Michigan Medicine including the Medical School, Dental School, University Health Service or the Mary A. Rackham Institute.  This includes those working remotely and temporary workers.   More information on this new policy is available on the U-M Health Response.

U-M EEO/AA Statement

The University of Michigan is an equal opportunity/affirmative action employer.