How to Apply
A cover letter is required for consideration for this position and should be attached as the first page of your resume. The cover letter should address your specific interest in the position and outline skills and experience that directly relate to this position.
An exciting opportunity has been created for an experienced researcher to join the Alumkal Laboratory (https://alumkal.lab.medicine.umich.edu/) at the U of M Division of Heme-Onc and the Rogel Cancer Center in Ann Arbor, MI. The individual will join as a Research Lab Specialist Associate and work as a Lab Manager, directly with Dr. Joshi Alumkal, Leader of the U of M Prostate/Genitourinary Oncology Cancer Section. He/she will be an integral member of a research team whose focus is epigenetics and drug resistance in prostate cancer.
Our laboratory focuses on identifying mechanisms by which key chromatin modifying enzymes and chromatin readers drive transcription of pathways that promote treatment resistance. We use genomics studies in prostate cancer clinical samples and prostate cancer cell line model systems and functional studies to understand this process. Our goal is to develop new, targeted treatment strategies for men with advanced prostate cancer.
The Lab Manager will be responsible for managing laboratory operations, including: regulatory aspects such as IBC and IACUC; equipment maintenance and service contracts; and project management involving sample coordination, shipping, and processing. Ordering supplies, inventorying, and unpacking deliveries are also important responsibilities. This individual may also carry out experiments in the laboratory, including protein and RNA expression and purification from mammalian cells and bacteria, QPCR, Western blotting, tissue culture of mammalian cell lines and transfection, and may assist with mouse experiments.
Michigan Medicine improves the health of patients, populations and communities through excellence in education, patient care, community service, research and technology development, and through leadership activities in Michigan, nationally and internationally. Our mission is guided by our Strategic Principles and has three critical components; patient care, education and research that together enhance our contribution to society.
Why Work at Michigan?
Being part of something greater, of serving a larger mission of discovery and care — that's the heart of what drives people to work at Michigan. In some way, great or small, every person here helps to advance this world-class institution. It's adding a purpose to your profession. Work at Michigan and become a victor for the greater good.
- Orders and stocks supplies, maintains equipment, in charge of submitting and maintaining regulatory approvals (IACUC, IRB, IBC) related to our projects.
- Project management: sample coordination, processing, storage and inventory management, and shipping for some studies.
- Performs cell culture, molecular biology techniques including: DNA/RNA/protein extraction, QPCR, and Western blots, etc. Performs mouse xenograft tumor growth experiments with drug injections, drug gavage, tumor measurements.
- Additional laboratory duties as assigned by PI
- Bachelor's degree (4yr) with major courses in field of research, 1-3 years of experience, or an equivalent combination of education and experience may be accepted, including relevant undergraduate and graduate student experience
- Must be proficient with computers running Windows and PC applications (e.g. MS Excel, Word and PowerPoint).
- Master's degree is preferred.
- Greater than 2 years working in a laboratory environment post-college.
- Previous lab management skills.
- Strong organizational and multi-tasking skills.
- Excellent teamwork and communication skills.
- Knowledge and understanding of laboratory safety and ability to work carefully with potentially harmful agents.
- Prior experience with writing and maintaining IACUC and IBC protocols.
- Proficiency with mammalian cell culture and with molecular biology techniques such as RT-PCR, western blotting, cloning, and reporter gene analysis is preferred. Rodent handling experience, including injection and/or gavage treatment.
- Ability and willingness to learn and implement novel experimental techniques.
Michigan Medicine conducts background screening and pre-employment drug testing on job candidates upon acceptance of a contingent job offer and may use a third party administrator to conduct background screenings. Background screenings are performed in compliance with the Fair Credit Report Act. Pre-employment drug testing applies to all selected candidates, including new or additional faculty and staff appointments, as well as transfers from other U-M campuses.
Job openings are posted for a minimum of seven calendar days. The review and selection process may begin as early as the eighth day after posting. This opening may be removed from posting boards and filled anytime after the minimum posting period has ended.
U-M EEO/AA Statement
The University of Michigan is an equal opportunity/affirmative action employer.