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An exciting MALDI mass spectometry job opportunity has opened in the Wahl laboratory at the University of Michigan. We are a translational brain cancer research laboratory comprised of postdoctoral fellows, graduate students, research faculty and medical/undergraduate students. We develop new treatments in the research lab and bring these ideas to patients through clinical trials in collaboration with neuro-oncologists. We also study the biology of brain tumors in human patients through collaborations with our neurosurgery colleagues. We are developing a MALDI/spatial metabolomics platform and are seeking a motivated and hard-working scientist with excellent communication skills to work with laboratory team members to install and run our new spatial mass spectrometer.

Mission Statement

The mission of the University of Michigan is to serve the people of Michigan and the world through preeminence in creating, communicating, preserving and applying knowledge, art, and academic values, and in developing leaders and citizens who will challenge the present and enrich the future.


  • Manage the installation, quality assurance, operations and maintenance of a Bruker timsTOF flex MALDI2 spatial mass spectrometer and associated HPLC.
  • Manage the installation, quality assurance and operations of a matrix sprayer.
  • Optimize matrix deposition on tissues to maximize metabolite detection.
  • Maintain metabolite standard libraries to assist in feature identification.
  • Develop workflows and methods for spatial metabolomic analysis on cancer and normal tissues including isotope tracing pipelines and establish data storage and maintenance.
  • Coordinate tissue analysis with laboratory members (no experience/expertise in tissue sectioning is needed).
  • Develop multi-omic spatial analysis techniques to pair spatial metabolomic data with cellular identification using mass-tagged antibodies.

Required Qualifications*

  • PhD in chemistry or related field.
  • Expertise in analytical chemistry and mass spectrometry (MALDI experience not required).
  • Familiarity with complex data storage and analysis.
  • Outstanding communication skills.
  • Ability to work independently in a vibrant research lab environment.

Desired Qualifications*

  • Familiarity with complex data storage and analysis.
  • Superb interpersonal skills.
  • Strong work ethic.
  • Experience with metabolomics analysis.
  • Experience with MALDI techniques.

Background Screening

Michigan Medicine conducts background screening and pre-employment drug testing on job candidates upon acceptance of a contingent job offer and may use a third party administrator to conduct background screenings.  Background screenings are performed in compliance with the Fair Credit Report Act. Pre-employment drug testing applies to all selected candidates, including new or additional faculty and staff appointments, as well as transfers from other U-M campuses.

Application Deadline

Job openings are posted for a minimum of seven calendar days.  The review and selection process may begin as early as the eighth day after posting. This opening may be removed from posting boards and filled anytime after the minimum posting period has ended.

Vaccine Requirements

COVID-19 vaccinations are required for all students, faculty and staff working in the following areas: Michigan Medicine including the Medical School, Dental School, University Health Service or the Mary A. Rackham Institute.  This includes those working remotely and temporary workers.   More information on this new policy is available on the U-M Health Response.

U-M EEO/AA Statement

The University of Michigan is an equal opportunity/affirmative action employer.