Summary
The University of Michigan is offering a postdoctoral research position aimed at exploring the mechanisms contributing to vascular alterations, tissue fibrosis, and the complex interplay between the stroma and the immune system in the context of autoimmune diseases, specifically systemic sclerosis. This opportunity resides within a dynamic laboratory that maintains a tight coupling with clinical research programs to facilitate translational outcomes, epitomizing the bench-to-bedside philosophy.
The research focus emphasizes understanding how senescence in vascular endothelial cells influences intercellular communication, blood vessel changes, and tissue fibrosis. The position will leverage a combination of cutting-edge techniques that include but are not limited to cellular and animal models, transcriptomics, epigenetics, and a suite of biochemical assays.
We are on the lookout for a dynamic and self-motivated researcher who is ready to take a leading role in this project and contribute to the field while building their career at a prestigious institution.
Mission Statement
Michigan Medicine improves the health of patients, populations and communities through excellence in education, patient care, community service, research and technology development, and through leadership activities in Michigan, nationally and internationally. Our mission is guided by our Strategic Principles and has three critical components; patient care, education and research that together enhance our contribution to society.
Why Join Michigan Medicine?
Michigan Medicine is one of the largest health care complexes in the world and has been the site of many groundbreaking medical and technological advancements since the opening of the U-M Medical School in 1850. Michigan Medicine is comprised of over 30,000 employees and our vision is to attract, inspire, and develop outstanding people in medicine, sciences, and healthcare to become one of the world’s most distinguished academic health systems. In some way, great or small, every person here helps to advance this world-class institution. Work at Michigan Medicine and become a victor for the greater good.
What Benefits can you Look Forward to?
- Excellent medical, dental and vision coverage effective on your very first day
- 2:1 Match on retirement savings
Responsibilities*
- Lead and manage the daily operations associated with the research project
- Participate in publications and presentations as author or co-author
- Develop, adapt, and implement new research techniques and protocols
- Design and perform experiments; keep appropriate experimental records and documentation
- Analyze, interpret, summarize and compile data
- Operate and maintain equipment and instruments
- Develop figures, search scientific literature, assist in writing manuscripts, submit abstracts, and present data at local and national meetings
- Perform routine animal procedures after appropriate training
- Perform standard cell and molecular biology assays
- Spearhead new tools and technologies and interact with collaborators and other research team members
- Prepare data reports for weekly meeting with PI and bi-monthly reports for weekly lab meeting
- Attend educational sessions, such as relevant lectures and journal clubs
Required Qualifications*
Candidates should have obtained a PhD or MD degree recently and demonstrate an intrinsic motivation, strong communication skills, and the ability to resolve problems autonomously. The position calls for robust knowledge and hands-on experience in cell and molecular biology. Aptitude in computational tasks is also a requisite. Specifically, expertise in culturing primary human endothelial cells is mandatory. Familiarity with advanced techniques such as single-cell RNA-sequencing, CHIP-seq, RNA interference strategies, flow cytometry, Western blotting, and ELISA will be favorably viewed. A comprehensive foundation in immunology, pharmacology, and sequencing methodologies will be advantageous, especially when previously applied to research on autoimmunity. Organizational skills, an eye for detail, and the capacity to work independently are vital traits for this role. Excellent English proficiency is necessary for effective communication.
The opportunity is open to applicants of diverse backgrounds. Candidates must meet the eligibility requirements to work within the United States.
Background Screening
Michigan Medicine conducts background screening and pre-employment drug testing on job candidates upon acceptance of a contingent job offer and may use a third party administrator to conduct background screenings. Background screenings are performed in compliance with the Fair Credit Report Act. Pre-employment drug testing applies to all selected candidates, including new or additional faculty and staff appointments, as well as transfers from other U-M campuses.
Application Deadline
Job openings are posted for a minimum of seven calendar days. The review and selection process may begin as early as the eighth day after posting. This opening may be removed from posting boards and filled anytime after the minimum posting period has ended.
U-M EEO/AA Statement
The University of Michigan is an equal opportunity/affirmative action employer.