How to Apply
A cover letter is required for consideration for this position and should be attached as the first page of your resume. The cover letter should address your specific interest in the position and outline skills and experience that directly relate to this position.
Job Summary
NOTE: This position is term-limited for one (1) year.
The laboratory of Jun Wu, at the Life Sciences Institute, is looking for a Research Investigator to oversee a research project to study the role of cholinergic regulation of liver function and thermogenic beige fat function. Major goals include the characterization of liver and thermogenic fat function using a combination of cell and molecular biology and transgenic mouse engineering. These studies will require considerable expertise and research experiences in cell and molecular biology techniques, including primary cell culture (hepatocytes, inguinal stromal vascular fractionation), mouse glucose tolerance test, oral gavage, real-time quantitative PCR (qRT-PCR), gene expression and protein analyses and functional assays for characterizing liver and fat function. In addition to planning and performing experiments, you will oversee research performed by undergraduate students. You will report directly to Dr. Jun Wu and will work full-time onsite.
Mission Statement
The Life Sciences Institute explores biological processes, structures, and functions at the finest scale to create impact on a global scale.
For more information on the Wu laboratory: https://www.lsi.umich.edu/science/our-labs/wu-lab
Responsibilities*
Experimental responsibilities will include:
- Design experiments in collaboration with others
- Primary cell culture, including primary hepatocytes, primary inguinal stromal vascular fractionation
- Maintain mammalian cell cultures and stocks
- Manage transgenic mouse colony
- Perform metabolic characterization of mouse study, including glucose tolerance test, insulin tolerance test, oral gavage
- Perform quantitative analyses and communicate findings through reports and summaries
- Solve experimental problems that arise in any of the responsibilities
Non-experimental responsibilities will include:
- Provide consultation and advice to lab members in areas of expertise
- Maintain clear laboratory notebooks
- Provide detailed documentation so experiments can be replicated
- Follow laboratory best practices for safety and quality
- Help manage projects
- Assist PI in preparing manuscripts and grants
Required Qualifications*
- Ph.D. in molecular biology, cell biology, biochemistry, or related discipline
- Minimum 5 years of experience of postdoctoral work
- Minimum 5 years of experience in cell and molecular biology techniques, including real-time quantitative PCR (qRT-PCR), gene expression and protein analyses and functional assays for characterizing metabolic function.
- Minimum 5 years of experience managing transgenic mouse colony
- Minimum 5 years of experience mentoring students
- Strong publication record in relevant work
- Prior experience working in a collaborative environment
Desired Qualifications*
- Minimum 5 years of experience characterizing mouse transgenic models
Modes of Work
Positions that are eligible for hybrid or mobile/remote work mode are at the discretion of the hiring department. Work agreements are reviewed annually at a minimum and are subject to change at any time, and for any reason, throughout the course of employment. Learn more about the work modes.
Additional Information
Benefits at the University of Michigan
In addition to a career filled with purpose and opportunity, The University of Michigan offers a comprehensive benefits package to help you stay well, protect yourself and your family and plan for a secure future. Benefits include:
- A retirement plan that provides two-for-one matching contributions
- Many choices for comprehensive health insurance
- Dental and Vision Insurance
- Life insurance
- Long-term disability coverage
- Flexible spending accounts for healthcare and dependent care expenses
- Maternity and Parental Leave
Background Screening
The University of Michigan conducts background checks on all job candidates upon acceptance of a contingent offer and may use a third party administrator to conduct background checks. Background checks are performed in compliance with the Fair Credit Reporting Act.
Application Deadline
All applications for this position must be received by 11:59p, Thursday, May 1st.
U-M EEO Statement
The University of Michigan is an equal employment opportunity employer.