How to Apply
A cover letter is required. Please specifically detail any relevant hands-on experience with mouse cardiovascular or cerebrovascular recovery surgeries (e.g., TAC, MI, MCAO, etc) to be considered.
Job Summary
The research laboratory of Dr. Anthony Rosenzweig in the Department of Internal Medicine, Division of Cardiovascular Medicine at the University of Michigan, Ann Arbor, MI is seeking an experienced mouse surgeon to perform advanced microsurgical procedures for preclinical research. The ideal candidate will establish and maintain complex disease models, including Transverse Aortic Constriction (TAC), Myocardial Infarction (MI), Ischemia-Reperfusion Injury (IRI), Middle Cerebral Artery Occlusion (MCAO), and other stroke or cardiovascular models. The successful candidate will become a critical contributor and collaborator on translational studies uncovering the shared mechanisms driving health and disease in the heart and brain.
The Rosenzweig Lab is located within the Frankel Institute of Heart and Brain Health at Michigan Medicine?s North Campus Research Complex, a newly renovated facility designed to foster collaboration and innovation. Our team is at the forefront of exploring shared mechanisms between the heart and brain and how these organs communicate in health and disease. With rapidly expanding research needs, we offer a diverse and evolving portfolio that includes surgical and exercise models, general procedures, and newly integrated neurocognitive and behavioral testing capabilities. You will have access to state-of-the-art resources and a vibrant network of skilled collaborators dedicated to advancing cardiovascular and neurovascular science.
Mission Statement
Michigan Medicine improves the health of patients, populations and communities through excellence in education, patient care, community service, research and technology development, and through leadership activities in Michigan, nationally and internationally. Our mission is guided by our Strategic Principles and has three critical components; patient care, education and research that together enhance our contribution to society.
Why Join Michigan Medicine?
Michigan Medicine is one of the largest health care complexes in the world and has been the site of many groundbreaking medical and technological advancements since the opening of the U-M Medical School in 1850. Michigan Medicine is comprised of over 30,000 employees and our vision is to attract, inspire, and develop outstanding people in medicine, sciences, and healthcare to become one of the world?s most distinguished academic health systems. In some way, great or small, every person here helps to advance this world-class institution. Work at Michigan Medicine and become a victor for the greater good.
What Benefits can you Look Forward to?
- Excellent medical, dental and vision coverage effective on your very first day
- 2:1 Match on retirement savings
Responsibilities*
We are seeking candidates with a passion for science with the potential to substantively impact our understanding of health and disease. The successful candidate must have outstanding surgical technique and act as the resident expert in cardiac and brain animal models, providing input into the design and implementation of key in vivo experiments by working in close collaboration with the PI and other lab personnel. This role involves a combination of project consultation planning with lab members, hands-on animal work, care and monitoring of animals post-surgery, and record keeping, all currently conducted under approved research protocols.
- Advanced Microsurgery & Model Development: Perform precise procedures (TAC, MI, IRI, MCAO) and collaborate with the PI and other senior lab personnel to design new research projects and surgical protocols.
- Post-Operative & Specialized Care: Oversee perioperative care, recovery monitoring, and cardiomyocyte isolation from adult/neonatal rodents.
- Lab Leadership & Compliance: Act as the "resident expert," training junior staff, managing SOP development, and ensuring 100% compliance with IACUC guidelines.
- Operations & Data Management: Maintain meticulous surgical records, manage surgical consumables through Quartzy, and contribute to data analysis.
Required Qualifications*
Senior Level
- Bachelor's degree
- 5-6 years of related experience including mouse/rat recovery surgeries with strong knowledge of aseptic technique and perioperative care
- Proven experience in rodent microsurgery, specifically TAC, MI, IRI, MCAO, or similar models.
- 4+ years of experience in mouse tissue collection and injections (subcutaneous and intraperitoneal).
- Excellent attention to detail and manual dexterity.
- Familiarity with regulatory requirements for animal research.
- A strong work ethic, great organization, excellent communication skills, and the ability to work effectively in a team environment.
- An advanced understanding and commitment to animal care and management
Intermediate Level
- Bachelor's degree
- 4-5 years experience
Associate Level
- Bachelor's degree
- 1-3 years experience
Desired Qualifications*
All levels
- Experience isolating cardiomyocytes from adult and neonatal mouse and rat hearts
- Ability to perform murine echocardiography or a willingness to learn
- Ability to learn new cardiovascular and/or brain models.
- Prior experience in a research-intensive environment.
- Knowledge and experience managing mouse breeding and genotyping
- Experience managing mouse colony with tracking software
- Advanced degree (e.g., DVM, PhD) is helpful but not essential.
Work Schedule
- This is a full-time position M-F onsite at NCRC with a preferred work schedule of 8:30-4:30pm.
- Flexibility in hours may be arranged in order to be present to complete job responsibilities.
Modes of Work
Positions that are eligible for hybrid or mobile/remote work mode are at the discretion of the hiring department. Work agreements are reviewed annually at a minimum and are subject to change at any time, and for any reason, throughout the course of employment. Learn more about the work modes.
Underfill Statement
This position may be underfilled at a lower classification depending on the qualifications of the selected candidate.
Background Screening
Michigan Medicine conducts background screening and pre-employment drug testing on job candidates upon acceptance of a contingent job offer and may use a third party administrator to conduct background screenings. Background screenings are performed in compliance with the Fair Credit Report Act. Pre-employment drug testing applies to all selected candidates, including new or additional faculty and staff appointments, as well as transfers from other U-M campuses.
Application Deadline
Job openings are posted for a minimum of seven calendar days. The review and selection process may begin as early as the eighth day after posting. This opening may be removed from posting boards and filled anytime after the minimum posting period has ended.
U-M EEO Statement
The University of Michigan is an equal employment opportunity employer.