How to Apply
A cover letter is required for consideration for this position and should be attached as the first page of your resume. The cover letter should address your specific interest in the position and outline skills and experience that directly relate to this position.
Interested applicants should apply directly to Dr. Mosalaganti by sending the following: (1) Cover Letter (indicating future project interests); (2) Curriculum Vitae (CV); and (3) Contact information for three references to [email protected].
Mission Statement
The Life Sciences Institute explores biological processes, structures, and functions at the finest scale to create impact on a global scale.
For more information on the Mosalaganti laboratory: https://www.lsi.umich.edu/science/our-labs/mosalaganti-lab
Job Summary
The Mosalaganti lab at the Life Sciences Institute (LSI) is seeking an outstanding postdoctoral research fellow interested in using in situ cryo-electron tomography (cryo-ET) in conjunction with cryo-CLEM to address membrane remodeling events. You will have unencumbered access to our Leica Stellaris cryo-confocal, Aquilos2, Titan Krios G4i (with K3, BioQuantum imaging filter, and phase plate) housed on-site. Candidates should have the following: (1) a strong background in structural biology/biophysics, (2) a sense of independence, and (3) be motivated to push the boundaries of structural biology. You will report directly to Dr. Mosalaganti and perform your work onsite at the LSI.
Responsibilities*
Experimental responsibilities will include:
- Cryo-CLEM, cryo-FIB, and cryo-ET analyses of cell lines.
- Morphometric analysis, subtomogram averaging, and integrative structural and computational analysis.
- Serial lift-out from patient tissue samples and organoid models of disease.
Non-Experimental responsibilities will include:
- Work with PI to apply for independent research funding.
- Work/collaborate with other postdoctoral fellows and graduate students in and outside of the laboratory.
- Mentor undergraduates and graduate students in the laboratory.
- Assist PI with writing manuscripts and grants.
Required Qualifications*
- Ph.D. in chemistry, physics, or a related discipline
- Minimum of two (2) years of experience in cryo-ET data collection and processing
- Ability to work independently and as a team player
- Excellent communication skills
Desired Qualifications*
- Minimum of 2 years of experience in continuous heterogeneity analysis and integrative modeling.
Modes of Work
Positions that are eligible for hybrid or mobile/remote work mode are at the discretion of the hiring department. Work agreements are reviewed annually at a minimum and are subject to change at any time, and for any reason, throughout the course of employment. Learn more about the work modes.
Additional Information
Recent graduates or students finishing their graduate studies this year/early next year can apply for an exciting fellowship through the Michigan Life Science Fellowship program (https://lifescifellows.umich.edu/).
For more information, please contact Dr. Mosalaganti at [email protected]
Pursuant to University policy, postdoctoral research fellow appointments should be for one year or less, with the possibility of renewal in subsequent years, not to exceed a total of five years of postdoctoral training at the University.
Benefits at the University of Michigan:
The University of Michigan offers a comprehensive benefits package to help you stay well, protect yourself and your family and plan for a secure future. Benefits include:
Many choices for comprehensive health insurance
Dental and Vision Insurance
Life insurance
Flexible spending accounts for healthcare and dependent care expenses
Maternity and Parental Leave
Background Screening
The University of Michigan conducts background checks on all job candidates upon acceptance of a contingent offer and may use a third party administrator to conduct background checks. Background checks are performed in compliance with the Fair Credit Reporting Act.
Application Deadline
Job openings are posted for a minimum of seven calendar days. The review and selection process may begin as early as the eighth day after posting. This opening may be removed from posting boards and filled any time after the minimum posting period has ended.
U-M EEO Statement
The University of Michigan is an Equal Opportunity Employer. We are committed to providing an environment of mutual respect where equal employment opportunities are available to all applicants, including protected veterans and individuals with disabilities.